Recombinant multi-species YTHDC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YTHDC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]
The Alternative Names of target: 3'-5' RNA helicase YTHDC2,3010002F02Rik,CAHL,RGD1563192,YTH domain-containing protein 2 (hYTHDC2),YTHDC2,Ythdc2,hYTHDC2,mYTHDC2

Target products collectionGo to YTHDC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11354-Ag-1/ GM-Tg-hg-IP11354-Ag-2 Human YTHDC2 protein Human
GM-Tg-rg-IP11354-Ag-1/ GM-Tg-rg-IP11354-Ag-2 Rat YTHDC2 protein Rat
GM-Tg-mg-IP11354-Ag-1/ GM-Tg-mg-IP11354-Ag-2 Mouse YTHDC2 protein Mouse
GM-Tg-cynog-IP11354-Ag-1/ GM-Tg-cynog-IP11354-Ag-2 Cynomolgus/Rhesus macaque YTHDC2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11354-Ag-1/ GM-Tg-felg-IP11354-Ag-2 Feline YTHDC2 protein Feline
GM-Tg-cang-IP11354-Ag-1/ GM-Tg-cang-IP11354-Ag-2 Canine YTHDC2 protein Canine
GM-Tg-bovg-IP11354-Ag-1/ GM-Tg-bovg-IP11354-Ag-2 Bovine YTHDC2 protein Bovine
GM-Tg-equg-IP11354-Ag-1/ GM-Tg-equg-IP11354-Ag-2 Equine YTHDC2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11354-Ag-1/ GM-Tg-hg-IP11354-Ag-2; GM-Tg-rg-IP11354-Ag-1/ GM-Tg-rg-IP11354-Ag-2;
GM-Tg-mg-IP11354-Ag-1/ GM-Tg-mg-IP11354-Ag-2; GM-Tg-cynog-IP11354-Ag-1/ GM-Tg-cynog-IP11354-Ag-2;
GM-Tg-felg-IP11354-Ag-1/ GM-Tg-felg-IP11354-Ag-2; GM-Tg-cang-IP11354-Ag-1/ GM-Tg-cang-IP11354-Ag-2;
GM-Tg-bovg-IP11354-Ag-1/ GM-Tg-bovg-IP11354-Ag-2; GM-Tg-equg-IP11354-Ag-1/ GM-Tg-equg-IP11354-Ag-2
Products Name YTHDC2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name YTHDC2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YTHDC2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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