Recombinant multi-species NMNAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NMNAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15. [provided by RefSeq, Jul 2014]
The Alternative Names of target: 2610529L11Rik,5730441G13Rik,D4Cole1e,LCA9,NMN/NaMN adenylyltransferase 1,NMNAT,NMNAT1,Nicotinamide-nucleotide adenylyltransferase 1 (NMN adenylyltransferase 1),Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1,Nicotinate-nucleotide adenylyltransferase 1 (NaMN adenylyltransferase 1),Nmnat1,PNAT1,SHILCA,nmnat

Target products collectionGo to NMNAT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11351-Ag-1/ GM-Tg-hg-IP11351-Ag-2 Human NMNAT1 protein Human
GM-Tg-rg-IP11351-Ag-1/ GM-Tg-rg-IP11351-Ag-2 Rat NMNAT1 protein Rat
GM-Tg-mg-IP11351-Ag-1/ GM-Tg-mg-IP11351-Ag-2 Mouse NMNAT1 protein Mouse
GM-Tg-cynog-IP11351-Ag-1/ GM-Tg-cynog-IP11351-Ag-2 Cynomolgus/Rhesus macaque NMNAT1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11351-Ag-1/ GM-Tg-felg-IP11351-Ag-2 Feline NMNAT1 protein Feline
GM-Tg-cang-IP11351-Ag-1/ GM-Tg-cang-IP11351-Ag-2 Canine NMNAT1 protein Canine
GM-Tg-bovg-IP11351-Ag-1/ GM-Tg-bovg-IP11351-Ag-2 Bovine NMNAT1 protein Bovine
GM-Tg-equg-IP11351-Ag-1/ GM-Tg-equg-IP11351-Ag-2 Equine NMNAT1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11351-Ag-1/ GM-Tg-hg-IP11351-Ag-2; GM-Tg-rg-IP11351-Ag-1/ GM-Tg-rg-IP11351-Ag-2;
GM-Tg-mg-IP11351-Ag-1/ GM-Tg-mg-IP11351-Ag-2; GM-Tg-cynog-IP11351-Ag-1/ GM-Tg-cynog-IP11351-Ag-2;
GM-Tg-felg-IP11351-Ag-1/ GM-Tg-felg-IP11351-Ag-2; GM-Tg-cang-IP11351-Ag-1/ GM-Tg-cang-IP11351-Ag-2;
GM-Tg-bovg-IP11351-Ag-1/ GM-Tg-bovg-IP11351-Ag-2; GM-Tg-equg-IP11351-Ag-1/ GM-Tg-equg-IP11351-Ag-2
Products Name NMNAT1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NMNAT1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NMNAT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.