Recombinant multi-species DCLRE1C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DCLRE1C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
The Alternative Names of target: 9930121L06Rik,A-SCID,Art,DCLRE1C,DCLREC1C,DNA cross-link repair 1C protein,Dclre1c,Protein A-SCID,Protein artemis,RS-SCID,SCIDA,SNM1 homolog C (hSNM1C),SNM1-like protein,SNM1C,Snm1l
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP11217-Ag-1/ GM-Tg-hg-IP11217-Ag-2 | Human DCLRE1C protein | Human |
| GM-Tg-rg-IP11217-Ag-1/ GM-Tg-rg-IP11217-Ag-2 | Rat DCLRE1C protein | Rat |
| GM-Tg-mg-IP11217-Ag-1/ GM-Tg-mg-IP11217-Ag-2 | Mouse DCLRE1C protein | Mouse |
| GM-Tg-cynog-IP11217-Ag-1/ GM-Tg-cynog-IP11217-Ag-2 | Cynomolgus/Rhesus macaque DCLRE1C protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP11217-Ag-1/ GM-Tg-felg-IP11217-Ag-2 | Feline DCLRE1C protein | Feline |
| GM-Tg-cang-IP11217-Ag-1/ GM-Tg-cang-IP11217-Ag-2 | Canine DCLRE1C protein | Canine |
| GM-Tg-bovg-IP11217-Ag-1/ GM-Tg-bovg-IP11217-Ag-2 | Bovine DCLRE1C protein | Bovine |
| GM-Tg-equg-IP11217-Ag-1/ GM-Tg-equg-IP11217-Ag-2 | Equine DCLRE1C protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP11217-Ag-1/ GM-Tg-hg-IP11217-Ag-2;
GM-Tg-rg-IP11217-Ag-1/ GM-Tg-rg-IP11217-Ag-2;
GM-Tg-mg-IP11217-Ag-1/ GM-Tg-mg-IP11217-Ag-2; GM-Tg-cynog-IP11217-Ag-1/ GM-Tg-cynog-IP11217-Ag-2; GM-Tg-felg-IP11217-Ag-1/ GM-Tg-felg-IP11217-Ag-2; GM-Tg-cang-IP11217-Ag-1/ GM-Tg-cang-IP11217-Ag-2; GM-Tg-bovg-IP11217-Ag-1/ GM-Tg-bovg-IP11217-Ag-2; GM-Tg-equg-IP11217-Ag-1/ GM-Tg-equg-IP11217-Ag-2 |
| Products Name | DCLRE1C protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DCLRE1C |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DCLRE1C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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characterized by high binding affinity,
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Through
expression in mammalian cell lines, GMab has
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myriad domains of biological drug
discovery, encompassing cellular cultivation,
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strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.