Recombinant multi-species SFRS2/SRSF2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SFRS2/SRSF2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq, Sep 2010]
The Alternative Names of target: 35 kDa,D11Wsu175e,MRF-1,PR264,Pr264,Protein PR264,SC-35,SC35,SFRS2,SFRS2A,SRSF2,SRp30b,Serine/arginine-rich splicing factor 2,Sfrs10,Sfrs2,Splicing component,Splicing factor,Splicing factor SC35 (SC-35),Srsf2,arginine/serine-rich 2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP11151-Ag-1/ GM-Tg-hg-IP11151-Ag-2 | Human SFRS2/SRSF2 protein | Human |
| GM-Tg-rg-IP11151-Ag-1/ GM-Tg-rg-IP11151-Ag-2 | Rat SFRS2/SRSF2 protein | Rat |
| GM-Tg-mg-IP11151-Ag-1/ GM-Tg-mg-IP11151-Ag-2 | Mouse SFRS2/SRSF2 protein | Mouse |
| GM-Tg-cynog-IP11151-Ag-1/ GM-Tg-cynog-IP11151-Ag-2 | Cynomolgus/Rhesus macaque SFRS2/SRSF2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP11151-Ag-1/ GM-Tg-felg-IP11151-Ag-2 | Feline SFRS2/SRSF2 protein | Feline |
| GM-Tg-cang-IP11151-Ag-1/ GM-Tg-cang-IP11151-Ag-2 | Canine SFRS2/SRSF2 protein | Canine |
| GM-Tg-bovg-IP11151-Ag-1/ GM-Tg-bovg-IP11151-Ag-2 | Bovine SFRS2/SRSF2 protein | Bovine |
| GM-Tg-equg-IP11151-Ag-1/ GM-Tg-equg-IP11151-Ag-2 | Equine SFRS2/SRSF2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP11151-Ag-1/ GM-Tg-hg-IP11151-Ag-2;
GM-Tg-rg-IP11151-Ag-1/ GM-Tg-rg-IP11151-Ag-2;
GM-Tg-mg-IP11151-Ag-1/ GM-Tg-mg-IP11151-Ag-2; GM-Tg-cynog-IP11151-Ag-1/ GM-Tg-cynog-IP11151-Ag-2; GM-Tg-felg-IP11151-Ag-1/ GM-Tg-felg-IP11151-Ag-2; GM-Tg-cang-IP11151-Ag-1/ GM-Tg-cang-IP11151-Ag-2; GM-Tg-bovg-IP11151-Ag-1/ GM-Tg-bovg-IP11151-Ag-2; GM-Tg-equg-IP11151-Ag-1/ GM-Tg-equg-IP11151-Ag-2 |
| Products Name | SFRS2/SRSF2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | SFRS2/SRSF2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SFRS2/SRSF2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.