Recombinant multi-species SFPQ protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SFPQ protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Enables DNA binding activity; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and regulation of transcription by RNA polymerase II. Acts upstream of or within double-strand break repair via homologous recombination. Located in chromatin; nuclear matrix; and paraspeckles. [provided by Alliance of Genome Resources, Feb 2025]
The Alternative Names of target: 100 kDa DNA-pairing protein (hPOMp100),100 kDa subunit,1110004P21Rik,2810416M14Rik,5730453G22Rik,9030402K04Rik,D4Ertd314e,DNA-binding p52/p100 complex,Gm12940,POMP100,PPP1R140,PSF,PTB-associated-splicing factor),Polypyrimidine tract-binding protein-associated-splicing factor (PSF,REP1,SFPQ,Sfpq,Splicing factor,proline- and glutamine-rich

Target products collectionGo to SFPQ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11131-Ag-1/ GM-Tg-hg-IP11131-Ag-2 Human SFPQ protein Human
GM-Tg-rg-IP11131-Ag-1/ GM-Tg-rg-IP11131-Ag-2 Rat SFPQ protein Rat
GM-Tg-mg-IP11131-Ag-1/ GM-Tg-mg-IP11131-Ag-2 Mouse SFPQ protein Mouse
GM-Tg-cynog-IP11131-Ag-1/ GM-Tg-cynog-IP11131-Ag-2 Cynomolgus/Rhesus macaque SFPQ protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11131-Ag-1/ GM-Tg-felg-IP11131-Ag-2 Feline SFPQ protein Feline
GM-Tg-cang-IP11131-Ag-1/ GM-Tg-cang-IP11131-Ag-2 Canine SFPQ protein Canine
GM-Tg-bovg-IP11131-Ag-1/ GM-Tg-bovg-IP11131-Ag-2 Bovine SFPQ protein Bovine
GM-Tg-equg-IP11131-Ag-1/ GM-Tg-equg-IP11131-Ag-2 Equine SFPQ protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11131-Ag-1/ GM-Tg-hg-IP11131-Ag-2; GM-Tg-rg-IP11131-Ag-1/ GM-Tg-rg-IP11131-Ag-2;
GM-Tg-mg-IP11131-Ag-1/ GM-Tg-mg-IP11131-Ag-2; GM-Tg-cynog-IP11131-Ag-1/ GM-Tg-cynog-IP11131-Ag-2;
GM-Tg-felg-IP11131-Ag-1/ GM-Tg-felg-IP11131-Ag-2; GM-Tg-cang-IP11131-Ag-1/ GM-Tg-cang-IP11131-Ag-2;
GM-Tg-bovg-IP11131-Ag-1/ GM-Tg-bovg-IP11131-Ag-2; GM-Tg-equg-IP11131-Ag-1/ GM-Tg-equg-IP11131-Ag-2
Products Name SFPQ protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SFPQ
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SFPQ protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.