Recombinant multi-species SET/TAF-I protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SET/TAF-I protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
The Alternative Names of target: 2610030F17Rik,2PP2A,5730420M11Rik,HLA-DR-associated protein II,I-2PP2A,I2PP2A,IGAAD,IPP2A2,Inhibitor of granzyme A-activated DNase (IGAAD),MRD58,PHAPII,Phosphatase 2A inhibitor I2PP2A (I-2PP2A),Protein SET,SET,Set,StF-IT-1,TAF-I,TAF-IBETA,Template-activating factor I (TAF-I)

Target products collectionGo to SET/TAF-I products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11127-Ag-1/ GM-Tg-hg-IP11127-Ag-2 Human SET/TAF-I protein Human
GM-Tg-rg-IP11127-Ag-1/ GM-Tg-rg-IP11127-Ag-2 Rat SET/TAF-I protein Rat
GM-Tg-mg-IP11127-Ag-1/ GM-Tg-mg-IP11127-Ag-2 Mouse SET/TAF-I protein Mouse
GM-Tg-cynog-IP11127-Ag-1/ GM-Tg-cynog-IP11127-Ag-2 Cynomolgus/Rhesus macaque SET/TAF-I protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11127-Ag-1/ GM-Tg-felg-IP11127-Ag-2 Feline SET/TAF-I protein Feline
GM-Tg-cang-IP11127-Ag-1/ GM-Tg-cang-IP11127-Ag-2 Canine SET/TAF-I protein Canine
GM-Tg-bovg-IP11127-Ag-1/ GM-Tg-bovg-IP11127-Ag-2 Bovine SET/TAF-I protein Bovine
GM-Tg-equg-IP11127-Ag-1/ GM-Tg-equg-IP11127-Ag-2 Equine SET/TAF-I protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11127-Ag-1/ GM-Tg-hg-IP11127-Ag-2; GM-Tg-rg-IP11127-Ag-1/ GM-Tg-rg-IP11127-Ag-2;
GM-Tg-mg-IP11127-Ag-1/ GM-Tg-mg-IP11127-Ag-2; GM-Tg-cynog-IP11127-Ag-1/ GM-Tg-cynog-IP11127-Ag-2;
GM-Tg-felg-IP11127-Ag-1/ GM-Tg-felg-IP11127-Ag-2; GM-Tg-cang-IP11127-Ag-1/ GM-Tg-cang-IP11127-Ag-2;
GM-Tg-bovg-IP11127-Ag-1/ GM-Tg-bovg-IP11127-Ag-2; GM-Tg-equg-IP11127-Ag-1/ GM-Tg-equg-IP11127-Ag-2
Products Name SET/TAF-I protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SET/TAF-I
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SET/TAF-I protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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