Recombinant multi-species LRIT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LRIT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F. [provided by RefSeq, May 2013]
The Alternative Names of target: CSNB1F,FIGLER4,Gm421,LRIT3,Leucine-rich repeat,Lrit3,RGD1559637,immunoglobulin-like domain and transmembrane domain-containing protein 3
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1110-Ag-1/ GM-Tg-hg-IP1110-Ag-2 | Human LRIT3 protein | Human |
| GM-Tg-rg-IP1110-Ag-1/ GM-Tg-rg-IP1110-Ag-2 | Rat LRIT3 protein | Rat |
| GM-Tg-mg-IP1110-Ag-1/ GM-Tg-mg-IP1110-Ag-2 | Mouse LRIT3 protein | Mouse |
| GM-Tg-cynog-IP1110-Ag-1/ GM-Tg-cynog-IP1110-Ag-2 | Cynomolgus/Rhesus macaque LRIT3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1110-Ag-1/ GM-Tg-felg-IP1110-Ag-2 | Feline LRIT3 protein | Feline |
| GM-Tg-cang-IP1110-Ag-1/ GM-Tg-cang-IP1110-Ag-2 | Canine LRIT3 protein | Canine |
| GM-Tg-bovg-IP1110-Ag-1/ GM-Tg-bovg-IP1110-Ag-2 | Bovine LRIT3 protein | Bovine |
| GM-Tg-equg-IP1110-Ag-1/ GM-Tg-equg-IP1110-Ag-2 | Equine LRIT3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP1110-Ag-1/ GM-Tg-hg-IP1110-Ag-2;
GM-Tg-rg-IP1110-Ag-1/ GM-Tg-rg-IP1110-Ag-2;
GM-Tg-mg-IP1110-Ag-1/ GM-Tg-mg-IP1110-Ag-2; GM-Tg-cynog-IP1110-Ag-1/ GM-Tg-cynog-IP1110-Ag-2; GM-Tg-felg-IP1110-Ag-1/ GM-Tg-felg-IP1110-Ag-2; GM-Tg-cang-IP1110-Ag-1/ GM-Tg-cang-IP1110-Ag-2; GM-Tg-bovg-IP1110-Ag-1/ GM-Tg-bovg-IP1110-Ag-2; GM-Tg-equg-IP1110-Ag-1/ GM-Tg-equg-IP1110-Ag-2 |
| Products Name | LRIT3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | LRIT3 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LRIT3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.