Recombinant multi-species LRIT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LRIT3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F. [provided by RefSeq, May 2013]
The Alternative Names of target: CSNB1F,FIGLER4,Gm421,LRIT3,Leucine-rich repeat,Lrit3,RGD1559637,immunoglobulin-like domain and transmembrane domain-containing protein 3

Target products collectionGo to LRIT3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1110-Ag-1/ GM-Tg-hg-IP1110-Ag-2 Human LRIT3 protein Human
GM-Tg-rg-IP1110-Ag-1/ GM-Tg-rg-IP1110-Ag-2 Rat LRIT3 protein Rat
GM-Tg-mg-IP1110-Ag-1/ GM-Tg-mg-IP1110-Ag-2 Mouse LRIT3 protein Mouse
GM-Tg-cynog-IP1110-Ag-1/ GM-Tg-cynog-IP1110-Ag-2 Cynomolgus/Rhesus macaque LRIT3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1110-Ag-1/ GM-Tg-felg-IP1110-Ag-2 Feline LRIT3 protein Feline
GM-Tg-cang-IP1110-Ag-1/ GM-Tg-cang-IP1110-Ag-2 Canine LRIT3 protein Canine
GM-Tg-bovg-IP1110-Ag-1/ GM-Tg-bovg-IP1110-Ag-2 Bovine LRIT3 protein Bovine
GM-Tg-equg-IP1110-Ag-1/ GM-Tg-equg-IP1110-Ag-2 Equine LRIT3 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1110-Ag-1/ GM-Tg-hg-IP1110-Ag-2; GM-Tg-rg-IP1110-Ag-1/ GM-Tg-rg-IP1110-Ag-2;
GM-Tg-mg-IP1110-Ag-1/ GM-Tg-mg-IP1110-Ag-2; GM-Tg-cynog-IP1110-Ag-1/ GM-Tg-cynog-IP1110-Ag-2;
GM-Tg-felg-IP1110-Ag-1/ GM-Tg-felg-IP1110-Ag-2; GM-Tg-cang-IP1110-Ag-1/ GM-Tg-cang-IP1110-Ag-2;
GM-Tg-bovg-IP1110-Ag-1/ GM-Tg-bovg-IP1110-Ag-2; GM-Tg-equg-IP1110-Ag-1/ GM-Tg-equg-IP1110-Ag-2
Products Name LRIT3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LRIT3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LRIT3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.