Recombinant multi-species RPS6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RPS6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 40S ribosomal protein S6,Phosphoprotein NP33,RPS6,Rps6,S6,S6R,Small ribosomal subunit protein eS6,eS6
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10998-Ag-1/ GM-Tg-hg-IP10998-Ag-2 | Human RPS6 protein | Human |
| GM-Tg-rg-IP10998-Ag-1/ GM-Tg-rg-IP10998-Ag-2 | Rat RPS6 protein | Rat |
| GM-Tg-mg-IP10998-Ag-1/ GM-Tg-mg-IP10998-Ag-2 | Mouse RPS6 protein | Mouse |
| GM-Tg-cynog-IP10998-Ag-1/ GM-Tg-cynog-IP10998-Ag-2 | Cynomolgus/Rhesus macaque RPS6 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10998-Ag-1/ GM-Tg-felg-IP10998-Ag-2 | Feline RPS6 protein | Feline |
| GM-Tg-cang-IP10998-Ag-1/ GM-Tg-cang-IP10998-Ag-2 | Canine RPS6 protein | Canine |
| GM-Tg-bovg-IP10998-Ag-1/ GM-Tg-bovg-IP10998-Ag-2 | Bovine RPS6 protein | Bovine |
| GM-Tg-equg-IP10998-Ag-1/ GM-Tg-equg-IP10998-Ag-2 | Equine RPS6 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10998-Ag-1/ GM-Tg-hg-IP10998-Ag-2;
GM-Tg-rg-IP10998-Ag-1/ GM-Tg-rg-IP10998-Ag-2;
GM-Tg-mg-IP10998-Ag-1/ GM-Tg-mg-IP10998-Ag-2; GM-Tg-cynog-IP10998-Ag-1/ GM-Tg-cynog-IP10998-Ag-2; GM-Tg-felg-IP10998-Ag-1/ GM-Tg-felg-IP10998-Ag-2; GM-Tg-cang-IP10998-Ag-1/ GM-Tg-cang-IP10998-Ag-2; GM-Tg-bovg-IP10998-Ag-1/ GM-Tg-bovg-IP10998-Ag-2; GM-Tg-equg-IP10998-Ag-1/ GM-Tg-equg-IP10998-Ag-2 |
| Products Name | RPS6 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RPS6 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RPS6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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GMab, developed by GeneMedi, constitutes an
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pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.