Recombinant multi-species RPS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RPS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
The Alternative Names of target: 40S ribosomal protein S3,D7Ertd795e,RPS3,Rps3,Rs_3,S3,Small ribosomal subunit protein uS3,uS3
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10990-Ag-1/ GM-Tg-hg-IP10990-Ag-2 | Human RPS3 protein | Human |
| GM-Tg-rg-IP10990-Ag-1/ GM-Tg-rg-IP10990-Ag-2 | Rat RPS3 protein | Rat |
| GM-Tg-mg-IP10990-Ag-1/ GM-Tg-mg-IP10990-Ag-2 | Mouse RPS3 protein | Mouse |
| GM-Tg-cynog-IP10990-Ag-1/ GM-Tg-cynog-IP10990-Ag-2 | Cynomolgus/Rhesus macaque RPS3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10990-Ag-1/ GM-Tg-felg-IP10990-Ag-2 | Feline RPS3 protein | Feline |
| GM-Tg-cang-IP10990-Ag-1/ GM-Tg-cang-IP10990-Ag-2 | Canine RPS3 protein | Canine |
| GM-Tg-bovg-IP10990-Ag-1/ GM-Tg-bovg-IP10990-Ag-2 | Bovine RPS3 protein | Bovine |
| GM-Tg-equg-IP10990-Ag-1/ GM-Tg-equg-IP10990-Ag-2 | Equine RPS3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10990-Ag-1/ GM-Tg-hg-IP10990-Ag-2;
GM-Tg-rg-IP10990-Ag-1/ GM-Tg-rg-IP10990-Ag-2;
GM-Tg-mg-IP10990-Ag-1/ GM-Tg-mg-IP10990-Ag-2; GM-Tg-cynog-IP10990-Ag-1/ GM-Tg-cynog-IP10990-Ag-2; GM-Tg-felg-IP10990-Ag-1/ GM-Tg-felg-IP10990-Ag-2; GM-Tg-cang-IP10990-Ag-1/ GM-Tg-cang-IP10990-Ag-2; GM-Tg-bovg-IP10990-Ag-1/ GM-Tg-bovg-IP10990-Ag-2; GM-Tg-equg-IP10990-Ag-1/ GM-Tg-equg-IP10990-Ag-2 |
| Products Name | RPS3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RPS3 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RPS3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
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exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.