Recombinant multi-species RPL5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RPL5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18P family of ribosomal proteins and component of the 60S subunit. The encoded protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The encoded protein may also function to inhibit tumorigenesis through the activation of downstream tumor suppressors and the downregulation of oncoprotein expression. Mutations in this gene have been identified in patients with Diamond-Blackfan Anemia (DBA). This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Mar 2017]
The Alternative Names of target: 60S ribosomal protein L5,L5,Large ribosomal subunit protein uL18,MSTP030,PPP1R135,RPL5,Rpl5,Ska23,Ska
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10958-Ag-1/ GM-Tg-hg-IP10958-Ag-2 | Human RPL5 protein | Human |
| GM-Tg-rg-IP10958-Ag-1/ GM-Tg-rg-IP10958-Ag-2 | Rat RPL5 protein | Rat |
| GM-Tg-mg-IP10958-Ag-1/ GM-Tg-mg-IP10958-Ag-2 | Mouse RPL5 protein | Mouse |
| GM-Tg-cynog-IP10958-Ag-1/ GM-Tg-cynog-IP10958-Ag-2 | Cynomolgus/Rhesus macaque RPL5 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10958-Ag-1/ GM-Tg-felg-IP10958-Ag-2 | Feline RPL5 protein | Feline |
| GM-Tg-cang-IP10958-Ag-1/ GM-Tg-cang-IP10958-Ag-2 | Canine RPL5 protein | Canine |
| GM-Tg-bovg-IP10958-Ag-1/ GM-Tg-bovg-IP10958-Ag-2 | Bovine RPL5 protein | Bovine |
| GM-Tg-equg-IP10958-Ag-1/ GM-Tg-equg-IP10958-Ag-2 | Equine RPL5 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10958-Ag-1/ GM-Tg-hg-IP10958-Ag-2;
GM-Tg-rg-IP10958-Ag-1/ GM-Tg-rg-IP10958-Ag-2;
GM-Tg-mg-IP10958-Ag-1/ GM-Tg-mg-IP10958-Ag-2; GM-Tg-cynog-IP10958-Ag-1/ GM-Tg-cynog-IP10958-Ag-2; GM-Tg-felg-IP10958-Ag-1/ GM-Tg-felg-IP10958-Ag-2; GM-Tg-cang-IP10958-Ag-1/ GM-Tg-cang-IP10958-Ag-2; GM-Tg-bovg-IP10958-Ag-1/ GM-Tg-bovg-IP10958-Ag-2; GM-Tg-equg-IP10958-Ag-1/ GM-Tg-equg-IP10958-Ag-2 |
| Products Name | RPL5 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RPL5 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RPL5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.