Recombinant multi-species GUF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GUF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
The Alternative Names of target: 4631409J12,DEE40,EF-4,EF4,EIEE40,Elongation factor 4 homolog (EF-4),GTPase GUF1,GUF1,Guf1,RGD1310774,Ribosomal back-translocase,Translation factor GUF1,mitochondrial,mtEF4

Target products collectionGo to GUF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10936-Ag-1/ GM-Tg-hg-IP10936-Ag-2 Human GUF1 protein Human
GM-Tg-rg-IP10936-Ag-1/ GM-Tg-rg-IP10936-Ag-2 Rat GUF1 protein Rat
GM-Tg-mg-IP10936-Ag-1/ GM-Tg-mg-IP10936-Ag-2 Mouse GUF1 protein Mouse
GM-Tg-cynog-IP10936-Ag-1/ GM-Tg-cynog-IP10936-Ag-2 Cynomolgus/Rhesus macaque GUF1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10936-Ag-1/ GM-Tg-felg-IP10936-Ag-2 Feline GUF1 protein Feline
GM-Tg-cang-IP10936-Ag-1/ GM-Tg-cang-IP10936-Ag-2 Canine GUF1 protein Canine
GM-Tg-bovg-IP10936-Ag-1/ GM-Tg-bovg-IP10936-Ag-2 Bovine GUF1 protein Bovine
GM-Tg-equg-IP10936-Ag-1/ GM-Tg-equg-IP10936-Ag-2 Equine GUF1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10936-Ag-1/ GM-Tg-hg-IP10936-Ag-2; GM-Tg-rg-IP10936-Ag-1/ GM-Tg-rg-IP10936-Ag-2;
GM-Tg-mg-IP10936-Ag-1/ GM-Tg-mg-IP10936-Ag-2; GM-Tg-cynog-IP10936-Ag-1/ GM-Tg-cynog-IP10936-Ag-2;
GM-Tg-felg-IP10936-Ag-1/ GM-Tg-felg-IP10936-Ag-2; GM-Tg-cang-IP10936-Ag-1/ GM-Tg-cang-IP10936-Ag-2;
GM-Tg-bovg-IP10936-Ag-1/ GM-Tg-bovg-IP10936-Ag-2; GM-Tg-equg-IP10936-Ag-1/ GM-Tg-equg-IP10936-Ag-2
Products Name GUF1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GUF1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GUF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.