Recombinant multi-species GUF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GUF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
The Alternative Names of target: 4631409J12,DEE40,EF-4,EF4,EIEE40,Elongation factor 4 homolog (EF-4),GTPase GUF1,GUF1,Guf1,RGD1310774,Ribosomal back-translocase,Translation factor GUF1,mitochondrial,mtEF4
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10936-Ag-1/ GM-Tg-hg-IP10936-Ag-2 | Human GUF1 protein | Human |
| GM-Tg-rg-IP10936-Ag-1/ GM-Tg-rg-IP10936-Ag-2 | Rat GUF1 protein | Rat |
| GM-Tg-mg-IP10936-Ag-1/ GM-Tg-mg-IP10936-Ag-2 | Mouse GUF1 protein | Mouse |
| GM-Tg-cynog-IP10936-Ag-1/ GM-Tg-cynog-IP10936-Ag-2 | Cynomolgus/Rhesus macaque GUF1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10936-Ag-1/ GM-Tg-felg-IP10936-Ag-2 | Feline GUF1 protein | Feline |
| GM-Tg-cang-IP10936-Ag-1/ GM-Tg-cang-IP10936-Ag-2 | Canine GUF1 protein | Canine |
| GM-Tg-bovg-IP10936-Ag-1/ GM-Tg-bovg-IP10936-Ag-2 | Bovine GUF1 protein | Bovine |
| GM-Tg-equg-IP10936-Ag-1/ GM-Tg-equg-IP10936-Ag-2 | Equine GUF1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10936-Ag-1/ GM-Tg-hg-IP10936-Ag-2;
GM-Tg-rg-IP10936-Ag-1/ GM-Tg-rg-IP10936-Ag-2;
GM-Tg-mg-IP10936-Ag-1/ GM-Tg-mg-IP10936-Ag-2; GM-Tg-cynog-IP10936-Ag-1/ GM-Tg-cynog-IP10936-Ag-2; GM-Tg-felg-IP10936-Ag-1/ GM-Tg-felg-IP10936-Ag-2; GM-Tg-cang-IP10936-Ag-1/ GM-Tg-cang-IP10936-Ag-2; GM-Tg-bovg-IP10936-Ag-1/ GM-Tg-bovg-IP10936-Ag-2; GM-Tg-equg-IP10936-Ag-1/ GM-Tg-equg-IP10936-Ag-2 |
| Products Name | GUF1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | GUF1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GUF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.