Recombinant multi-species LMBR1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LMBR1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1110048D14Rik,ACHP,C7orf2,DIF14,Differentiation-related gene 14 protein,LMBR1,LSS,Limb region 1 protein homolog,Lmbr1,PPD2,RGD1563910,THYP,TPT,TPTPS,ZRS

Target products collectionGo to LMBR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1093-Ag-1/ GM-Tg-hg-IP1093-Ag-2 Human LMBR1 protein Human
GM-Tg-rg-IP1093-Ag-1/ GM-Tg-rg-IP1093-Ag-2 Rat LMBR1 protein Rat
GM-Tg-mg-IP1093-Ag-1/ GM-Tg-mg-IP1093-Ag-2 Mouse LMBR1 protein Mouse
GM-Tg-cynog-IP1093-Ag-1/ GM-Tg-cynog-IP1093-Ag-2 Cynomolgus/Rhesus macaque LMBR1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1093-Ag-1/ GM-Tg-felg-IP1093-Ag-2 Feline LMBR1 protein Feline
GM-Tg-cang-IP1093-Ag-1/ GM-Tg-cang-IP1093-Ag-2 Canine LMBR1 protein Canine
GM-Tg-bovg-IP1093-Ag-1/ GM-Tg-bovg-IP1093-Ag-2 Bovine LMBR1 protein Bovine
GM-Tg-equg-IP1093-Ag-1/ GM-Tg-equg-IP1093-Ag-2 Equine LMBR1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1093-Ag-1/ GM-Tg-hg-IP1093-Ag-2; GM-Tg-rg-IP1093-Ag-1/ GM-Tg-rg-IP1093-Ag-2;
GM-Tg-mg-IP1093-Ag-1/ GM-Tg-mg-IP1093-Ag-2; GM-Tg-cynog-IP1093-Ag-1/ GM-Tg-cynog-IP1093-Ag-2;
GM-Tg-felg-IP1093-Ag-1/ GM-Tg-felg-IP1093-Ag-2; GM-Tg-cang-IP1093-Ag-1/ GM-Tg-cang-IP1093-Ag-2;
GM-Tg-bovg-IP1093-Ag-1/ GM-Tg-bovg-IP1093-Ag-2; GM-Tg-equg-IP1093-Ag-1/ GM-Tg-equg-IP1093-Ag-2
Products Name LMBR1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LMBR1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LMBR1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.