Recombinant multi-species RECQL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RECQL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer. [provided by RefSeq, Jan 2017]
The Alternative Names of target: ATP-dependent DNA helicase Q1,DNA 3'-5' helicase Q1,DNA helicase,DNA-dependent ATPase Q1,RECON,RECQL,RECQL1,RecQ protein-like 1,RecQ-like type 1 (RecQ1),RecQ1,Recql
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10886-Ag-1/ GM-Tg-hg-IP10886-Ag-2 | Human RECQL protein | Human |
| GM-Tg-rg-IP10886-Ag-1/ GM-Tg-rg-IP10886-Ag-2 | Rat RECQL protein | Rat |
| GM-Tg-mg-IP10886-Ag-1/ GM-Tg-mg-IP10886-Ag-2 | Mouse RECQL protein | Mouse |
| GM-Tg-cynog-IP10886-Ag-1/ GM-Tg-cynog-IP10886-Ag-2 | Cynomolgus/Rhesus macaque RECQL protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10886-Ag-1/ GM-Tg-felg-IP10886-Ag-2 | Feline RECQL protein | Feline |
| GM-Tg-cang-IP10886-Ag-1/ GM-Tg-cang-IP10886-Ag-2 | Canine RECQL protein | Canine |
| GM-Tg-bovg-IP10886-Ag-1/ GM-Tg-bovg-IP10886-Ag-2 | Bovine RECQL protein | Bovine |
| GM-Tg-equg-IP10886-Ag-1/ GM-Tg-equg-IP10886-Ag-2 | Equine RECQL protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10886-Ag-1/ GM-Tg-hg-IP10886-Ag-2;
GM-Tg-rg-IP10886-Ag-1/ GM-Tg-rg-IP10886-Ag-2;
GM-Tg-mg-IP10886-Ag-1/ GM-Tg-mg-IP10886-Ag-2; GM-Tg-cynog-IP10886-Ag-1/ GM-Tg-cynog-IP10886-Ag-2; GM-Tg-felg-IP10886-Ag-1/ GM-Tg-felg-IP10886-Ag-2; GM-Tg-cang-IP10886-Ag-1/ GM-Tg-cang-IP10886-Ag-2; GM-Tg-bovg-IP10886-Ag-1/ GM-Tg-bovg-IP10886-Ag-2; GM-Tg-equg-IP10886-Ag-1/ GM-Tg-equg-IP10886-Ag-2 |
| Products Name | RECQL protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RECQL |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RECQL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.