Recombinant multi-species RAD23B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RAD23B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011]
The Alternative Names of target: 0610007D13Rik,HHR23B,HR23B,P58,RAD23B,Rad23b,UV excision repair protein RAD23 homolog B,XP-C repair-complementing complex 58 kDa protein (p58),hHR23B,mHR23B,p58

Target products collectionGo to RAD23B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10837-Ag-1/ GM-Tg-hg-IP10837-Ag-2 Human RAD23B protein Human
GM-Tg-rg-IP10837-Ag-1/ GM-Tg-rg-IP10837-Ag-2 Rat RAD23B protein Rat
GM-Tg-mg-IP10837-Ag-1/ GM-Tg-mg-IP10837-Ag-2 Mouse RAD23B protein Mouse
GM-Tg-cynog-IP10837-Ag-1/ GM-Tg-cynog-IP10837-Ag-2 Cynomolgus/Rhesus macaque RAD23B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10837-Ag-1/ GM-Tg-felg-IP10837-Ag-2 Feline RAD23B protein Feline
GM-Tg-cang-IP10837-Ag-1/ GM-Tg-cang-IP10837-Ag-2 Canine RAD23B protein Canine
GM-Tg-bovg-IP10837-Ag-1/ GM-Tg-bovg-IP10837-Ag-2 Bovine RAD23B protein Bovine
GM-Tg-equg-IP10837-Ag-1/ GM-Tg-equg-IP10837-Ag-2 Equine RAD23B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10837-Ag-1/ GM-Tg-hg-IP10837-Ag-2; GM-Tg-rg-IP10837-Ag-1/ GM-Tg-rg-IP10837-Ag-2;
GM-Tg-mg-IP10837-Ag-1/ GM-Tg-mg-IP10837-Ag-2; GM-Tg-cynog-IP10837-Ag-1/ GM-Tg-cynog-IP10837-Ag-2;
GM-Tg-felg-IP10837-Ag-1/ GM-Tg-felg-IP10837-Ag-2; GM-Tg-cang-IP10837-Ag-1/ GM-Tg-cang-IP10837-Ag-2;
GM-Tg-bovg-IP10837-Ag-1/ GM-Tg-bovg-IP10837-Ag-2; GM-Tg-equg-IP10837-Ag-1/ GM-Tg-equg-IP10837-Ag-2
Products Name RAD23B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RAD23B
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RAD23B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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