Recombinant multi-species PEX5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PEX5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
The Alternative Names of target: ESTM1,PBD2A,PBD2B,PEX5,PTS1 receptor,PTS1-BP,PTS1R,PXR1,PXR1P,Peroxin-5,Peroxisomal C-terminal targeting signal import receptor,Peroxisomal targeting signal 1 receptor,Peroxisome receptor 1,Pex5,Pxr1,RCDP5

Target products collectionGo to PEX5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10777-Ag-1/ GM-Tg-hg-IP10777-Ag-2 Human PEX5 protein Human
GM-Tg-rg-IP10777-Ag-1/ GM-Tg-rg-IP10777-Ag-2 Rat PEX5 protein Rat
GM-Tg-mg-IP10777-Ag-1/ GM-Tg-mg-IP10777-Ag-2 Mouse PEX5 protein Mouse
GM-Tg-cynog-IP10777-Ag-1/ GM-Tg-cynog-IP10777-Ag-2 Cynomolgus/Rhesus macaque PEX5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10777-Ag-1/ GM-Tg-felg-IP10777-Ag-2 Feline PEX5 protein Feline
GM-Tg-cang-IP10777-Ag-1/ GM-Tg-cang-IP10777-Ag-2 Canine PEX5 protein Canine
GM-Tg-bovg-IP10777-Ag-1/ GM-Tg-bovg-IP10777-Ag-2 Bovine PEX5 protein Bovine
GM-Tg-equg-IP10777-Ag-1/ GM-Tg-equg-IP10777-Ag-2 Equine PEX5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10777-Ag-1/ GM-Tg-hg-IP10777-Ag-2; GM-Tg-rg-IP10777-Ag-1/ GM-Tg-rg-IP10777-Ag-2;
GM-Tg-mg-IP10777-Ag-1/ GM-Tg-mg-IP10777-Ag-2; GM-Tg-cynog-IP10777-Ag-1/ GM-Tg-cynog-IP10777-Ag-2;
GM-Tg-felg-IP10777-Ag-1/ GM-Tg-felg-IP10777-Ag-2; GM-Tg-cang-IP10777-Ag-1/ GM-Tg-cang-IP10777-Ag-2;
GM-Tg-bovg-IP10777-Ag-1/ GM-Tg-bovg-IP10777-Ag-2; GM-Tg-equg-IP10777-Ag-1/ GM-Tg-equg-IP10777-Ag-2
Products Name PEX5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PEX5
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PEX5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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