Recombinant multi-species GBA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GBA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cytosolic enzyme that can hydrolyze several types of glycosides. The enzyme has its highest activity at neutral pH and is predominantly expressed in human liver, kidney, intestine, and spleen. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2022]
The Alternative Names of target: CBG,CBGL1,Cytosolic beta-glucosidase,Cytosolic beta-glucosidase-like protein 1,Cytosolic galactosylceramidase,Cytosolic glucosylceramidase,Cytosolic glycosylceramidase (Cytosolic GCase),GBA3,GLUC,Glucosidase beta acid 3,Glucosylceramidase beta 3,KLRP,Klotho-related protein (KLrP)

Target products collectionGo to GBA3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10741-Ag-1/ GM-Tg-hg-IP10741-Ag-2 Human GBA3 protein Human
GM-Tg-rg-IP10741-Ag-1/ GM-Tg-rg-IP10741-Ag-2 Rat GBA3 protein Rat
GM-Tg-mg-IP10741-Ag-1/ GM-Tg-mg-IP10741-Ag-2 Mouse GBA3 protein Mouse
GM-Tg-cynog-IP10741-Ag-1/ GM-Tg-cynog-IP10741-Ag-2 Cynomolgus/Rhesus macaque GBA3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10741-Ag-1/ GM-Tg-felg-IP10741-Ag-2 Feline GBA3 protein Feline
GM-Tg-cang-IP10741-Ag-1/ GM-Tg-cang-IP10741-Ag-2 Canine GBA3 protein Canine
GM-Tg-bovg-IP10741-Ag-1/ GM-Tg-bovg-IP10741-Ag-2 Bovine GBA3 protein Bovine
GM-Tg-equg-IP10741-Ag-1/ GM-Tg-equg-IP10741-Ag-2 Equine GBA3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10741-Ag-1/ GM-Tg-hg-IP10741-Ag-2; GM-Tg-rg-IP10741-Ag-1/ GM-Tg-rg-IP10741-Ag-2;
GM-Tg-mg-IP10741-Ag-1/ GM-Tg-mg-IP10741-Ag-2; GM-Tg-cynog-IP10741-Ag-1/ GM-Tg-cynog-IP10741-Ag-2;
GM-Tg-felg-IP10741-Ag-1/ GM-Tg-felg-IP10741-Ag-2; GM-Tg-cang-IP10741-Ag-1/ GM-Tg-cang-IP10741-Ag-2;
GM-Tg-bovg-IP10741-Ag-1/ GM-Tg-bovg-IP10741-Ag-2; GM-Tg-equg-IP10741-Ag-1/ GM-Tg-equg-IP10741-Ag-2
Products Name GBA3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GBA3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GBA3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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