Recombinant multi-species GBA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GBA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AD035,Beta-glucocerebrosidase 2 (Beta-glucosidase 2),Bile acid beta-glucosidase GBA2,Bile acid glucosyl transferase GBA2,Cholesterol glucosyltransferase GBA2,Cholesteryl-beta-glucosidase GBA2,F630034E04,GBA2,Gba2,Glucosylceramidase 2,NLGase,Non-lysosomal cholesterol glycosyltransferase,Non-lysosomal galactosylceramidase,Non-lysosomal glucosylceramidase,Non-lysosomal glycosylceramidase,SPG46

Target products collectionGo to GBA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10729-Ag-1/ GM-Tg-hg-IP10729-Ag-2 Human GBA2 protein Human
GM-Tg-rg-IP10729-Ag-1/ GM-Tg-rg-IP10729-Ag-2 Rat GBA2 protein Rat
GM-Tg-mg-IP10729-Ag-1/ GM-Tg-mg-IP10729-Ag-2 Mouse GBA2 protein Mouse
GM-Tg-cynog-IP10729-Ag-1/ GM-Tg-cynog-IP10729-Ag-2 Cynomolgus/Rhesus macaque GBA2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10729-Ag-1/ GM-Tg-felg-IP10729-Ag-2 Feline GBA2 protein Feline
GM-Tg-cang-IP10729-Ag-1/ GM-Tg-cang-IP10729-Ag-2 Canine GBA2 protein Canine
GM-Tg-bovg-IP10729-Ag-1/ GM-Tg-bovg-IP10729-Ag-2 Bovine GBA2 protein Bovine
GM-Tg-equg-IP10729-Ag-1/ GM-Tg-equg-IP10729-Ag-2 Equine GBA2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10729-Ag-1/ GM-Tg-hg-IP10729-Ag-2; GM-Tg-rg-IP10729-Ag-1/ GM-Tg-rg-IP10729-Ag-2;
GM-Tg-mg-IP10729-Ag-1/ GM-Tg-mg-IP10729-Ag-2; GM-Tg-cynog-IP10729-Ag-1/ GM-Tg-cynog-IP10729-Ag-2;
GM-Tg-felg-IP10729-Ag-1/ GM-Tg-felg-IP10729-Ag-2; GM-Tg-cang-IP10729-Ag-1/ GM-Tg-cang-IP10729-Ag-2;
GM-Tg-bovg-IP10729-Ag-1/ GM-Tg-bovg-IP10729-Ag-2; GM-Tg-equg-IP10729-Ag-1/ GM-Tg-equg-IP10729-Ag-2
Products Name GBA2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GBA2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GBA2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.