Recombinant multi-species TMEM27/CLTRN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMEM27/CLTRN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
The Alternative Names of target: 0610008J07Rik,CLTRN,Cltrn,Collectrin,NX-17,NX17,Nx17,TMEM27,Tmem27,Transmembrane protein 27,collectrin
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10585-Ag-1/ GM-Tg-hg-IP10585-Ag-2 | Human TMEM27/CLTRN protein | Human |
| GM-Tg-rg-IP10585-Ag-1/ GM-Tg-rg-IP10585-Ag-2 | Rat TMEM27/CLTRN protein | Rat |
| GM-Tg-mg-IP10585-Ag-1/ GM-Tg-mg-IP10585-Ag-2 | Mouse TMEM27/CLTRN protein | Mouse |
| GM-Tg-cynog-IP10585-Ag-1/ GM-Tg-cynog-IP10585-Ag-2 | Cynomolgus/Rhesus macaque TMEM27/CLTRN protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10585-Ag-1/ GM-Tg-felg-IP10585-Ag-2 | Feline TMEM27/CLTRN protein | Feline |
| GM-Tg-cang-IP10585-Ag-1/ GM-Tg-cang-IP10585-Ag-2 | Canine TMEM27/CLTRN protein | Canine |
| GM-Tg-bovg-IP10585-Ag-1/ GM-Tg-bovg-IP10585-Ag-2 | Bovine TMEM27/CLTRN protein | Bovine |
| GM-Tg-equg-IP10585-Ag-1/ GM-Tg-equg-IP10585-Ag-2 | Equine TMEM27/CLTRN protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10585-Ag-1/ GM-Tg-hg-IP10585-Ag-2;
GM-Tg-rg-IP10585-Ag-1/ GM-Tg-rg-IP10585-Ag-2;
GM-Tg-mg-IP10585-Ag-1/ GM-Tg-mg-IP10585-Ag-2; GM-Tg-cynog-IP10585-Ag-1/ GM-Tg-cynog-IP10585-Ag-2; GM-Tg-felg-IP10585-Ag-1/ GM-Tg-felg-IP10585-Ag-2; GM-Tg-cang-IP10585-Ag-1/ GM-Tg-cang-IP10585-Ag-2; GM-Tg-bovg-IP10585-Ag-1/ GM-Tg-bovg-IP10585-Ag-2; GM-Tg-equg-IP10585-Ag-1/ GM-Tg-equg-IP10585-Ag-2 |
| Products Name | TMEM27/CLTRN protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | TMEM27/CLTRN |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TMEM27/CLTRN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
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monoclonal antibodies, each meticulously
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myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.