Recombinant multi-species PSMD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PSMD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. [provided by RefSeq, Jul 2012]
The Alternative Names of target: 26S proteasome non-ATPase regulatory subunit 3,26S proteasome regulatory subunit RPN3,26S proteasome regulatory subunit S3,AntP91a,D11Bwg1349e,P58,PSMD3,Proteasome subunit p58,Psd3,Psmd3,RPN3,S3,TSTA2,Tstap91a

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10522-Ag-1/ GM-Tg-hg-IP10522-Ag-2 Human PSMD3 protein Human
GM-Tg-rg-IP10522-Ag-1/ GM-Tg-rg-IP10522-Ag-2 Rat PSMD3 protein Rat
GM-Tg-mg-IP10522-Ag-1/ GM-Tg-mg-IP10522-Ag-2 Mouse PSMD3 protein Mouse
GM-Tg-cynog-IP10522-Ag-1/ GM-Tg-cynog-IP10522-Ag-2 Cynomolgus/Rhesus macaque PSMD3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10522-Ag-1/ GM-Tg-felg-IP10522-Ag-2 Feline PSMD3 protein Feline
GM-Tg-cang-IP10522-Ag-1/ GM-Tg-cang-IP10522-Ag-2 Canine PSMD3 protein Canine
GM-Tg-bovg-IP10522-Ag-1/ GM-Tg-bovg-IP10522-Ag-2 Bovine PSMD3 protein Bovine
GM-Tg-equg-IP10522-Ag-1/ GM-Tg-equg-IP10522-Ag-2 Equine PSMD3 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10522-Ag-1/ GM-Tg-hg-IP10522-Ag-2; GM-Tg-rg-IP10522-Ag-1/ GM-Tg-rg-IP10522-Ag-2;
GM-Tg-mg-IP10522-Ag-1/ GM-Tg-mg-IP10522-Ag-2; GM-Tg-cynog-IP10522-Ag-1/ GM-Tg-cynog-IP10522-Ag-2;
GM-Tg-felg-IP10522-Ag-1/ GM-Tg-felg-IP10522-Ag-2; GM-Tg-cang-IP10522-Ag-1/ GM-Tg-cang-IP10522-Ag-2;
GM-Tg-bovg-IP10522-Ag-1/ GM-Tg-bovg-IP10522-Ag-2; GM-Tg-equg-IP10522-Ag-1/ GM-Tg-equg-IP10522-Ag-2
Products Name PSMD3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PSMD3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PSMD3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.