Recombinant multi-species PSMD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PSMD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. [provided by RefSeq, Jul 2012]
The Alternative Names of target: 26S proteasome non-ATPase regulatory subunit 3,26S proteasome regulatory subunit RPN3,26S proteasome regulatory subunit S3,AntP91a,D11Bwg1349e,P58,PSMD3,Proteasome subunit p58,Psd3,Psmd3,RPN3,S3,TSTA2,Tstap91a
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10522-Ag-1/ GM-Tg-hg-IP10522-Ag-2 | Human PSMD3 protein | Human |
| GM-Tg-rg-IP10522-Ag-1/ GM-Tg-rg-IP10522-Ag-2 | Rat PSMD3 protein | Rat |
| GM-Tg-mg-IP10522-Ag-1/ GM-Tg-mg-IP10522-Ag-2 | Mouse PSMD3 protein | Mouse |
| GM-Tg-cynog-IP10522-Ag-1/ GM-Tg-cynog-IP10522-Ag-2 | Cynomolgus/Rhesus macaque PSMD3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10522-Ag-1/ GM-Tg-felg-IP10522-Ag-2 | Feline PSMD3 protein | Feline |
| GM-Tg-cang-IP10522-Ag-1/ GM-Tg-cang-IP10522-Ag-2 | Canine PSMD3 protein | Canine |
| GM-Tg-bovg-IP10522-Ag-1/ GM-Tg-bovg-IP10522-Ag-2 | Bovine PSMD3 protein | Bovine |
| GM-Tg-equg-IP10522-Ag-1/ GM-Tg-equg-IP10522-Ag-2 | Equine PSMD3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10522-Ag-1/ GM-Tg-hg-IP10522-Ag-2;
GM-Tg-rg-IP10522-Ag-1/ GM-Tg-rg-IP10522-Ag-2;
GM-Tg-mg-IP10522-Ag-1/ GM-Tg-mg-IP10522-Ag-2; GM-Tg-cynog-IP10522-Ag-1/ GM-Tg-cynog-IP10522-Ag-2; GM-Tg-felg-IP10522-Ag-1/ GM-Tg-felg-IP10522-Ag-2; GM-Tg-cang-IP10522-Ag-1/ GM-Tg-cang-IP10522-Ag-2; GM-Tg-bovg-IP10522-Ag-1/ GM-Tg-bovg-IP10522-Ag-2; GM-Tg-equg-IP10522-Ag-1/ GM-Tg-equg-IP10522-Ag-2 |
| Products Name | PSMD3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PSMD3 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PSMD3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.