Recombinant multi-species CABC1/COQ8A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CABC1/COQ8A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 4632432J16Rik,ADCK3,ARCA2,Adck3,Atypical kinase COQ8A,CABC1,COQ10D4,COQ8,COQ8A,Cabc1,Chaperone activity of bc1 complex-like (Chaperone-ABC1-like),Coenzyme Q protein 8A,Coq8a,SCAR9,aarF domain-containing protein kinase 3,mKIAA0451,mitochondrial

Target products collectionGo to CABC1/COQ8A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10497-Ag-1/ GM-Tg-hg-IP10497-Ag-2 Human CABC1/COQ8A protein Human
GM-Tg-rg-IP10497-Ag-1/ GM-Tg-rg-IP10497-Ag-2 Rat CABC1/COQ8A protein Rat
GM-Tg-mg-IP10497-Ag-1/ GM-Tg-mg-IP10497-Ag-2 Mouse CABC1/COQ8A protein Mouse
GM-Tg-cynog-IP10497-Ag-1/ GM-Tg-cynog-IP10497-Ag-2 Cynomolgus/Rhesus macaque CABC1/COQ8A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10497-Ag-1/ GM-Tg-felg-IP10497-Ag-2 Feline CABC1/COQ8A protein Feline
GM-Tg-cang-IP10497-Ag-1/ GM-Tg-cang-IP10497-Ag-2 Canine CABC1/COQ8A protein Canine
GM-Tg-bovg-IP10497-Ag-1/ GM-Tg-bovg-IP10497-Ag-2 Bovine CABC1/COQ8A protein Bovine
GM-Tg-equg-IP10497-Ag-1/ GM-Tg-equg-IP10497-Ag-2 Equine CABC1/COQ8A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10497-Ag-1/ GM-Tg-hg-IP10497-Ag-2; GM-Tg-rg-IP10497-Ag-1/ GM-Tg-rg-IP10497-Ag-2;
GM-Tg-mg-IP10497-Ag-1/ GM-Tg-mg-IP10497-Ag-2; GM-Tg-cynog-IP10497-Ag-1/ GM-Tg-cynog-IP10497-Ag-2;
GM-Tg-felg-IP10497-Ag-1/ GM-Tg-felg-IP10497-Ag-2; GM-Tg-cang-IP10497-Ag-1/ GM-Tg-cang-IP10497-Ag-2;
GM-Tg-bovg-IP10497-Ag-1/ GM-Tg-bovg-IP10497-Ag-2; GM-Tg-equg-IP10497-Ag-1/ GM-Tg-equg-IP10497-Ag-2
Products Name CABC1/COQ8A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CABC1/COQ8A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CABC1/COQ8A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.