Recombinant multi-species PSMB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PSMB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
The Alternative Names of target: C7-I,D4Wsu33e,HC7-I,Macropain subunit C7-I,Multicatalytic endopeptidase complex subunit C7-I,PSMB2,Proteasome component C7-I,Proteasome subunit beta type-2,Proteasome subunit beta-4 (beta-4),Psmb2

Target products collectionGo to PSMB2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10451-Ag-1/ GM-Tg-hg-IP10451-Ag-2 Human PSMB2 protein Human
GM-Tg-rg-IP10451-Ag-1/ GM-Tg-rg-IP10451-Ag-2 Rat PSMB2 protein Rat
GM-Tg-mg-IP10451-Ag-1/ GM-Tg-mg-IP10451-Ag-2 Mouse PSMB2 protein Mouse
GM-Tg-cynog-IP10451-Ag-1/ GM-Tg-cynog-IP10451-Ag-2 Cynomolgus/Rhesus macaque PSMB2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10451-Ag-1/ GM-Tg-felg-IP10451-Ag-2 Feline PSMB2 protein Feline
GM-Tg-cang-IP10451-Ag-1/ GM-Tg-cang-IP10451-Ag-2 Canine PSMB2 protein Canine
GM-Tg-bovg-IP10451-Ag-1/ GM-Tg-bovg-IP10451-Ag-2 Bovine PSMB2 protein Bovine
GM-Tg-equg-IP10451-Ag-1/ GM-Tg-equg-IP10451-Ag-2 Equine PSMB2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10451-Ag-1/ GM-Tg-hg-IP10451-Ag-2; GM-Tg-rg-IP10451-Ag-1/ GM-Tg-rg-IP10451-Ag-2;
GM-Tg-mg-IP10451-Ag-1/ GM-Tg-mg-IP10451-Ag-2; GM-Tg-cynog-IP10451-Ag-1/ GM-Tg-cynog-IP10451-Ag-2;
GM-Tg-felg-IP10451-Ag-1/ GM-Tg-felg-IP10451-Ag-2; GM-Tg-cang-IP10451-Ag-1/ GM-Tg-cang-IP10451-Ag-2;
GM-Tg-bovg-IP10451-Ag-1/ GM-Tg-bovg-IP10451-Ag-2; GM-Tg-equg-IP10451-Ag-1/ GM-Tg-equg-IP10451-Ag-2
Products Name PSMB2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PSMB2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PSMB2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.