Recombinant multi-species NPLOC4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NPLOC4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Predicted to enable ubiquitin binding activity and ubiquitin protein ligase binding activity. Predicted to contribute to K48-linked polyubiquitin modification-dependent protein binding activity and K63-linked polyubiquitin modification-dependent protein binding activity. Involved in negative regulation of RIG-I signaling pathway; negative regulation of type I interferon production; and proteolysis involved in protein catabolic process. Located in nucleus. Part of UFD1-NPL4 complex and VCP-NPL4-UFD1 AAA ATPase complex. [provided by Alliance of Genome Resources, Feb 2025]
The Alternative Names of target: NPL4,NPLOC4,Npl4,Nploc4,Nuclear protein localization protein 4 homolog,Protein NPL4,mKIAA1499

Target products collectionGo to NPLOC4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10231-Ag-1/ GM-Tg-hg-IP10231-Ag-2 Human NPLOC4 protein Human
GM-Tg-rg-IP10231-Ag-1/ GM-Tg-rg-IP10231-Ag-2 Rat NPLOC4 protein Rat
GM-Tg-mg-IP10231-Ag-1/ GM-Tg-mg-IP10231-Ag-2 Mouse NPLOC4 protein Mouse
GM-Tg-cynog-IP10231-Ag-1/ GM-Tg-cynog-IP10231-Ag-2 Cynomolgus/Rhesus macaque NPLOC4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10231-Ag-1/ GM-Tg-felg-IP10231-Ag-2 Feline NPLOC4 protein Feline
GM-Tg-cang-IP10231-Ag-1/ GM-Tg-cang-IP10231-Ag-2 Canine NPLOC4 protein Canine
GM-Tg-bovg-IP10231-Ag-1/ GM-Tg-bovg-IP10231-Ag-2 Bovine NPLOC4 protein Bovine
GM-Tg-equg-IP10231-Ag-1/ GM-Tg-equg-IP10231-Ag-2 Equine NPLOC4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10231-Ag-1/ GM-Tg-hg-IP10231-Ag-2; GM-Tg-rg-IP10231-Ag-1/ GM-Tg-rg-IP10231-Ag-2;
GM-Tg-mg-IP10231-Ag-1/ GM-Tg-mg-IP10231-Ag-2; GM-Tg-cynog-IP10231-Ag-1/ GM-Tg-cynog-IP10231-Ag-2;
GM-Tg-felg-IP10231-Ag-1/ GM-Tg-felg-IP10231-Ag-2; GM-Tg-cang-IP10231-Ag-1/ GM-Tg-cang-IP10231-Ag-2;
GM-Tg-bovg-IP10231-Ag-1/ GM-Tg-bovg-IP10231-Ag-2; GM-Tg-equg-IP10231-Ag-1/ GM-Tg-equg-IP10231-Ag-2
Products Name NPLOC4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NPLOC4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NPLOC4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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