Recombinant multi-species PPP3CC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP3CC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
The Alternative Names of target: CALNA3,CAM-PRP catalytic subunit,CNA3,Calcineurin,Calmodulin-dependent calcineurin A subunit gamma isoform,Calnc,PP2BA gamma,PP2Bgamma,PPP3CC,Ppp3cc,Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform,testis-specific catalytic subunit
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP10125-Ag-1/ GM-Tg-hg-IP10125-Ag-2 | Human PPP3CC protein | Human |
| GM-Tg-rg-IP10125-Ag-1/ GM-Tg-rg-IP10125-Ag-2 | Rat PPP3CC protein | Rat |
| GM-Tg-mg-IP10125-Ag-1/ GM-Tg-mg-IP10125-Ag-2 | Mouse PPP3CC protein | Mouse |
| GM-Tg-cynog-IP10125-Ag-1/ GM-Tg-cynog-IP10125-Ag-2 | Cynomolgus/Rhesus macaque PPP3CC protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP10125-Ag-1/ GM-Tg-felg-IP10125-Ag-2 | Feline PPP3CC protein | Feline |
| GM-Tg-cang-IP10125-Ag-1/ GM-Tg-cang-IP10125-Ag-2 | Canine PPP3CC protein | Canine |
| GM-Tg-bovg-IP10125-Ag-1/ GM-Tg-bovg-IP10125-Ag-2 | Bovine PPP3CC protein | Bovine |
| GM-Tg-equg-IP10125-Ag-1/ GM-Tg-equg-IP10125-Ag-2 | Equine PPP3CC protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP10125-Ag-1/ GM-Tg-hg-IP10125-Ag-2;
GM-Tg-rg-IP10125-Ag-1/ GM-Tg-rg-IP10125-Ag-2;
GM-Tg-mg-IP10125-Ag-1/ GM-Tg-mg-IP10125-Ag-2; GM-Tg-cynog-IP10125-Ag-1/ GM-Tg-cynog-IP10125-Ag-2; GM-Tg-felg-IP10125-Ag-1/ GM-Tg-felg-IP10125-Ag-2; GM-Tg-cang-IP10125-Ag-1/ GM-Tg-cang-IP10125-Ag-2; GM-Tg-bovg-IP10125-Ag-1/ GM-Tg-bovg-IP10125-Ag-2; GM-Tg-equg-IP10125-Ag-1/ GM-Tg-equg-IP10125-Ag-2 |
| Products Name | PPP3CC protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PPP3CC |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP3CC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.