Recombinant multi-species NUDT15 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NUDT15 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Apr 2016]
The Alternative Names of target: 6530403O17,A730068G11Rik,MTH2,MutT homolog 2 (MTH2),NUDT15,NUDT15D,Nucleoside diphosphate-linked moiety X motif 15 (Nudix motif 15),Nucleoside diphosphate-linked to another moiety X hydrolase 15 (Nudix hydrolase 15),Nucleotide triphosphate diphosphatase NUDT15,Nudt15

Target products collectionGo to NUDT15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10086-Ag-1/ GM-Tg-hg-IP10086-Ag-2 Human NUDT15 protein Human
GM-Tg-rg-IP10086-Ag-1/ GM-Tg-rg-IP10086-Ag-2 Rat NUDT15 protein Rat
GM-Tg-mg-IP10086-Ag-1/ GM-Tg-mg-IP10086-Ag-2 Mouse NUDT15 protein Mouse
GM-Tg-cynog-IP10086-Ag-1/ GM-Tg-cynog-IP10086-Ag-2 Cynomolgus/Rhesus macaque NUDT15 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10086-Ag-1/ GM-Tg-felg-IP10086-Ag-2 Feline NUDT15 protein Feline
GM-Tg-cang-IP10086-Ag-1/ GM-Tg-cang-IP10086-Ag-2 Canine NUDT15 protein Canine
GM-Tg-bovg-IP10086-Ag-1/ GM-Tg-bovg-IP10086-Ag-2 Bovine NUDT15 protein Bovine
GM-Tg-equg-IP10086-Ag-1/ GM-Tg-equg-IP10086-Ag-2 Equine NUDT15 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10086-Ag-1/ GM-Tg-hg-IP10086-Ag-2; GM-Tg-rg-IP10086-Ag-1/ GM-Tg-rg-IP10086-Ag-2;
GM-Tg-mg-IP10086-Ag-1/ GM-Tg-mg-IP10086-Ag-2; GM-Tg-cynog-IP10086-Ag-1/ GM-Tg-cynog-IP10086-Ag-2;
GM-Tg-felg-IP10086-Ag-1/ GM-Tg-felg-IP10086-Ag-2; GM-Tg-cang-IP10086-Ag-1/ GM-Tg-cang-IP10086-Ag-2;
GM-Tg-bovg-IP10086-Ag-1/ GM-Tg-bovg-IP10086-Ag-2; GM-Tg-equg-IP10086-Ag-1/ GM-Tg-equg-IP10086-Ag-2
Products Name NUDT15 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NUDT15
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NUDT15 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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