Recombinant multi-species PPP2R1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP2R1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
The Alternative Names of target: 6330556D22Rik,HJS2,MRD36,Medium tumor antigen-associated 61 kDa protein,PP2A,PP2A subunit A isoform PR65-alpha,PP2A subunit A isoform R1-alpha,PP2A-Aalpha,PP2AA,PP2AAALPHA,PP2Aa,PPP2R1A,PR65,PR65A,Ppp2r1a,Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

Target products collectionGo to PPP2R1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP10031-Ag-1/ GM-Tg-hg-IP10031-Ag-2 Human PPP2R1A protein Human
GM-Tg-rg-IP10031-Ag-1/ GM-Tg-rg-IP10031-Ag-2 Rat PPP2R1A protein Rat
GM-Tg-mg-IP10031-Ag-1/ GM-Tg-mg-IP10031-Ag-2 Mouse PPP2R1A protein Mouse
GM-Tg-cynog-IP10031-Ag-1/ GM-Tg-cynog-IP10031-Ag-2 Cynomolgus/Rhesus macaque PPP2R1A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP10031-Ag-1/ GM-Tg-felg-IP10031-Ag-2 Feline PPP2R1A protein Feline
GM-Tg-cang-IP10031-Ag-1/ GM-Tg-cang-IP10031-Ag-2 Canine PPP2R1A protein Canine
GM-Tg-bovg-IP10031-Ag-1/ GM-Tg-bovg-IP10031-Ag-2 Bovine PPP2R1A protein Bovine
GM-Tg-equg-IP10031-Ag-1/ GM-Tg-equg-IP10031-Ag-2 Equine PPP2R1A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP10031-Ag-1/ GM-Tg-hg-IP10031-Ag-2; GM-Tg-rg-IP10031-Ag-1/ GM-Tg-rg-IP10031-Ag-2;
GM-Tg-mg-IP10031-Ag-1/ GM-Tg-mg-IP10031-Ag-2; GM-Tg-cynog-IP10031-Ag-1/ GM-Tg-cynog-IP10031-Ag-2;
GM-Tg-felg-IP10031-Ag-1/ GM-Tg-felg-IP10031-Ag-2; GM-Tg-cang-IP10031-Ag-1/ GM-Tg-cang-IP10031-Ag-2;
GM-Tg-bovg-IP10031-Ag-1/ GM-Tg-bovg-IP10031-Ag-2; GM-Tg-equg-IP10031-Ag-1/ GM-Tg-equg-IP10031-Ag-2
Products Name PPP2R1A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PPP2R1A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP2R1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.