Recombinant multi-species HBS1L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HBS1L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009]
The Alternative Names of target: 2810035F15Rik,EF-1a,ERFS,HBS1,HBS1-like protein,HBS1L,HSPC276,Hbs1l,eRF3c,eRFS
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0956-Ag-1/ GM-Tg-hg-IP0956-Ag-2 | Human HBS1L protein | Human |
| GM-Tg-rg-IP0956-Ag-1/ GM-Tg-rg-IP0956-Ag-2 | Rat HBS1L protein | Rat |
| GM-Tg-mg-IP0956-Ag-1/ GM-Tg-mg-IP0956-Ag-2 | Mouse HBS1L protein | Mouse |
| GM-Tg-cynog-IP0956-Ag-1/ GM-Tg-cynog-IP0956-Ag-2 | Cynomolgus/Rhesus macaque HBS1L protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0956-Ag-1/ GM-Tg-felg-IP0956-Ag-2 | Feline HBS1L protein | Feline |
| GM-Tg-cang-IP0956-Ag-1/ GM-Tg-cang-IP0956-Ag-2 | Canine HBS1L protein | Canine |
| GM-Tg-bovg-IP0956-Ag-1/ GM-Tg-bovg-IP0956-Ag-2 | Bovine HBS1L protein | Bovine |
| GM-Tg-equg-IP0956-Ag-1/ GM-Tg-equg-IP0956-Ag-2 | Equine HBS1L protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP0956-Ag-1/ GM-Tg-hg-IP0956-Ag-2;
GM-Tg-rg-IP0956-Ag-1/ GM-Tg-rg-IP0956-Ag-2;
GM-Tg-mg-IP0956-Ag-1/ GM-Tg-mg-IP0956-Ag-2; GM-Tg-cynog-IP0956-Ag-1/ GM-Tg-cynog-IP0956-Ag-2; GM-Tg-felg-IP0956-Ag-1/ GM-Tg-felg-IP0956-Ag-2; GM-Tg-cang-IP0956-Ag-1/ GM-Tg-cang-IP0956-Ag-2; GM-Tg-bovg-IP0956-Ag-1/ GM-Tg-bovg-IP0956-Ag-2; GM-Tg-equg-IP0956-Ag-1/ GM-Tg-equg-IP0956-Ag-2 |
| Products Name | HBS1L protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | HBS1L |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HBS1L protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.