Recombinant multi-species FIG4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FIG4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5-bisphosphate 5-phosphatase,A530089I17Rik,ALS11,BOP,BTOP,CMT4J,FIG4,Fig4,KIAA0274,Kiaa0274,Phosphatidylinositol 3,Polyphosphoinositide phosphatase,RGD1311375,SAC domain-containing protein 3,SAC3,Sac3,Serine-protein phosphatase FIG4,YVS,dJ249I4.1

Target products collectionGo to FIG4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0846-Ag-1/ GM-Tg-hg-IP0846-Ag-2 Human FIG4 protein Human
GM-Tg-rg-IP0846-Ag-1/ GM-Tg-rg-IP0846-Ag-2 Rat FIG4 protein Rat
GM-Tg-mg-IP0846-Ag-1/ GM-Tg-mg-IP0846-Ag-2 Mouse FIG4 protein Mouse
GM-Tg-cynog-IP0846-Ag-1/ GM-Tg-cynog-IP0846-Ag-2 Cynomolgus/Rhesus macaque FIG4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0846-Ag-1/ GM-Tg-felg-IP0846-Ag-2 Feline FIG4 protein Feline
GM-Tg-cang-IP0846-Ag-1/ GM-Tg-cang-IP0846-Ag-2 Canine FIG4 protein Canine
GM-Tg-bovg-IP0846-Ag-1/ GM-Tg-bovg-IP0846-Ag-2 Bovine FIG4 protein Bovine
GM-Tg-equg-IP0846-Ag-1/ GM-Tg-equg-IP0846-Ag-2 Equine FIG4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0846-Ag-1/ GM-Tg-hg-IP0846-Ag-2; GM-Tg-rg-IP0846-Ag-1/ GM-Tg-rg-IP0846-Ag-2;
GM-Tg-mg-IP0846-Ag-1/ GM-Tg-mg-IP0846-Ag-2; GM-Tg-cynog-IP0846-Ag-1/ GM-Tg-cynog-IP0846-Ag-2;
GM-Tg-felg-IP0846-Ag-1/ GM-Tg-felg-IP0846-Ag-2; GM-Tg-cang-IP0846-Ag-1/ GM-Tg-cang-IP0846-Ag-2;
GM-Tg-bovg-IP0846-Ag-1/ GM-Tg-bovg-IP0846-Ag-2; GM-Tg-equg-IP0846-Ag-1/ GM-Tg-equg-IP0846-Ag-2
Products Name FIG4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FIG4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FIG4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.