Recombinant multi-species FBXO18/FBH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FBXO18/FBH1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: DNA 3'-5' helicase 1,F-box DNA helicase 1,F-box only protein 18,FBH1,FBXO18,Fbh1,Fbx18,Fbxo18,hFBH1

Target products collectionGo to FBXO18/FBH1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0837-Ag-1/ GM-Tg-hg-IP0837-Ag-2 Human FBXO18/FBH1 protein Human
GM-Tg-rg-IP0837-Ag-1/ GM-Tg-rg-IP0837-Ag-2 Rat FBXO18/FBH1 protein Rat
GM-Tg-mg-IP0837-Ag-1/ GM-Tg-mg-IP0837-Ag-2 Mouse FBXO18/FBH1 protein Mouse
GM-Tg-cynog-IP0837-Ag-1/ GM-Tg-cynog-IP0837-Ag-2 Cynomolgus/Rhesus macaque FBXO18/FBH1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0837-Ag-1/ GM-Tg-felg-IP0837-Ag-2 Feline FBXO18/FBH1 protein Feline
GM-Tg-cang-IP0837-Ag-1/ GM-Tg-cang-IP0837-Ag-2 Canine FBXO18/FBH1 protein Canine
GM-Tg-bovg-IP0837-Ag-1/ GM-Tg-bovg-IP0837-Ag-2 Bovine FBXO18/FBH1 protein Bovine
GM-Tg-equg-IP0837-Ag-1/ GM-Tg-equg-IP0837-Ag-2 Equine FBXO18/FBH1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0837-Ag-1/ GM-Tg-hg-IP0837-Ag-2; GM-Tg-rg-IP0837-Ag-1/ GM-Tg-rg-IP0837-Ag-2;
GM-Tg-mg-IP0837-Ag-1/ GM-Tg-mg-IP0837-Ag-2; GM-Tg-cynog-IP0837-Ag-1/ GM-Tg-cynog-IP0837-Ag-2;
GM-Tg-felg-IP0837-Ag-1/ GM-Tg-felg-IP0837-Ag-2; GM-Tg-cang-IP0837-Ag-1/ GM-Tg-cang-IP0837-Ag-2;
GM-Tg-bovg-IP0837-Ag-1/ GM-Tg-bovg-IP0837-Ag-2; GM-Tg-equg-IP0837-Ag-1/ GM-Tg-equg-IP0837-Ag-2
Products Name FBXO18/FBH1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FBXO18/FBH1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FBXO18/FBH1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.