Recombinant multi-species DHCR7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHCR7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by cognitive disability, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Aug 2009]
The Alternative Names of target: 6-epoxide hydrolase subunit DHCR7,7-DHC reductase,7-dehydrocholesterol reductase,Cholesterol-5,DHCR7,Delta7-sterol reductase,Dhcr7,SLOS,Sterol Delta(7)-reductase,Sterol reductase SR-2

Target products collectionGo to DHCR7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0689-Ag-1/ GM-Tg-hg-IP0689-Ag-2 Human DHCR7 protein Human
GM-Tg-rg-IP0689-Ag-1/ GM-Tg-rg-IP0689-Ag-2 Rat DHCR7 protein Rat
GM-Tg-mg-IP0689-Ag-1/ GM-Tg-mg-IP0689-Ag-2 Mouse DHCR7 protein Mouse
GM-Tg-cynog-IP0689-Ag-1/ GM-Tg-cynog-IP0689-Ag-2 Cynomolgus/Rhesus macaque DHCR7 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0689-Ag-1/ GM-Tg-felg-IP0689-Ag-2 Feline DHCR7 protein Feline
GM-Tg-cang-IP0689-Ag-1/ GM-Tg-cang-IP0689-Ag-2 Canine DHCR7 protein Canine
GM-Tg-bovg-IP0689-Ag-1/ GM-Tg-bovg-IP0689-Ag-2 Bovine DHCR7 protein Bovine
GM-Tg-equg-IP0689-Ag-1/ GM-Tg-equg-IP0689-Ag-2 Equine DHCR7 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0689-Ag-1/ GM-Tg-hg-IP0689-Ag-2; GM-Tg-rg-IP0689-Ag-1/ GM-Tg-rg-IP0689-Ag-2;
GM-Tg-mg-IP0689-Ag-1/ GM-Tg-mg-IP0689-Ag-2; GM-Tg-cynog-IP0689-Ag-1/ GM-Tg-cynog-IP0689-Ag-2;
GM-Tg-felg-IP0689-Ag-1/ GM-Tg-felg-IP0689-Ag-2; GM-Tg-cang-IP0689-Ag-1/ GM-Tg-cang-IP0689-Ag-2;
GM-Tg-bovg-IP0689-Ag-1/ GM-Tg-bovg-IP0689-Ag-2; GM-Tg-equg-IP0689-Ag-1/ GM-Tg-equg-IP0689-Ag-2
Products Name DHCR7 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DHCR7
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHCR7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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