Recombinant multi-species CYP1A2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP1A2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CYP1A2,Cytochrome P450 1A2,CYPIA2, Cholesterol 25-hydroxylase, Cytochrome P(3)450, Cytochrome P450 4, Cytochrome P450-P3, Hydroperoxy icosatetraenoate dehydratase,CP12,CYPIA2,P3-450,P450(PA)

Target products collectionGo to CYP1A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0643-Ab-1/ GM-Tg-hg-IP0643-Ab-2 Human CYP1A2 protein Human
GM-Tg-rg-IP0643-Ab-1/ GM-Tg-rg-IP0643-Ab-2 Rat CYP1A2 protein Rat
GM-Tg-mg-IP0643-Ab-1/ GM-Tg-mg-IP0643-Ab-2 Mouse CYP1A2 protein Mouse
GM-Tg-cynog-IP0643-Ab-1/ GM-Tg-cynog-IP0643-Ab-2 Cynomolgus/Rhesus macaque CYP1A2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0643-Ab-1/ GM-Tg-felg-IP0643-Ab-2 Feline CYP1A2 protein Feline
GM-Tg-cang-IP0643-Ab-1/ GM-Tg-cang-IP0643-Ab-2 Canine CYP1A2 protein Canine
GM-Tg-bovg-IP0643-Ab-1/ GM-Tg-bovg-IP0643-Ab-2 Bovine CYP1A2 protein Bovine
GM-Tg-equg-IP0643-Ab-1/ GM-Tg-equg-IP0643-Ab-2 Equine CYP1A2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0643-Ab-1/ GM-Tg-hg-IP0643-Ab-2; GM-Tg-rg-IP0643-Ab-1/ GM-Tg-rg-IP0643-Ab-2;
GM-Tg-mg-IP0643-Ab-1/ GM-Tg-mg-IP0643-Ab-2; GM-Tg-cynog-IP0643-Ab-1/ GM-Tg-cynog-IP0643-Ab-2;
GM-Tg-felg-IP0643-Ab-1/ GM-Tg-felg-IP0643-Ab-2; GM-Tg-cang-IP0643-Ab-1/ GM-Tg-cang-IP0643-Ab-2;
GM-Tg-bovg-IP0643-Ab-1/ GM-Tg-bovg-IP0643-Ab-2; GM-Tg-equg-IP0643-Ab-1/ GM-Tg-equg-IP0643-Ab-2
Products Name CYP1A2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CYP1A2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP1A2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.