Recombinant multi-species COX6C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX6C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010]
The Alternative Names of target: COVIc,COX-VIc,COX6C,Cox6c,Cox6c2,Cytochrome c oxidase polypeptide VIc,Cytochrome c oxidase subunit 6C,LOC101096876
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP0602-Ag-1/ GM-Tg-hg-IP0602-Ag-2 | Human COX6C protein | Human |
GM-Tg-rg-IP0602-Ag-1/ GM-Tg-rg-IP0602-Ag-2 | Rat COX6C protein | Rat |
GM-Tg-mg-IP0602-Ag-1/ GM-Tg-mg-IP0602-Ag-2 | Mouse COX6C protein | Mouse |
GM-Tg-cynog-IP0602-Ag-1/ GM-Tg-cynog-IP0602-Ag-2 | Cynomolgus/Rhesus macaque COX6C protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP0602-Ag-1/ GM-Tg-felg-IP0602-Ag-2 | Feline COX6C protein | Feline |
GM-Tg-cang-IP0602-Ag-1/ GM-Tg-cang-IP0602-Ag-2 | Canine COX6C protein | Canine |
GM-Tg-bovg-IP0602-Ag-1/ GM-Tg-bovg-IP0602-Ag-2 | Bovine COX6C protein | Bovine |
GM-Tg-equg-IP0602-Ag-1/ GM-Tg-equg-IP0602-Ag-2 | Equine COX6C protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-IP0602-Ag-1/ GM-Tg-hg-IP0602-Ag-2;
GM-Tg-rg-IP0602-Ag-1/ GM-Tg-rg-IP0602-Ag-2;
GM-Tg-mg-IP0602-Ag-1/ GM-Tg-mg-IP0602-Ag-2; GM-Tg-cynog-IP0602-Ag-1/ GM-Tg-cynog-IP0602-Ag-2; GM-Tg-felg-IP0602-Ag-1/ GM-Tg-felg-IP0602-Ag-2; GM-Tg-cang-IP0602-Ag-1/ GM-Tg-cang-IP0602-Ag-2; GM-Tg-bovg-IP0602-Ag-1/ GM-Tg-bovg-IP0602-Ag-2; GM-Tg-equg-IP0602-Ag-1/ GM-Tg-equg-IP0602-Ag-2 |
Products Name | COX6C protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | COX6C |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX6C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.