Recombinant multi-species COX4I2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX4I2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]
The Alternative Names of target: COX4,COX4-2,COX4B,COX4I2,COX4L2,COXIV-2,Cox4b,Cox4i2,CoxIV-2,Cytochrome c oxidase subunit 4 isoform 2,Cytochrome c oxidase subunit IV isoform 2 (COX IV-2),dJ857M17.2,mitochondrial

Target products collectionGo to COX4I2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0600-Ag-1/ GM-Tg-hg-IP0600-Ag-2 Human COX4I2 protein Human
GM-Tg-rg-IP0600-Ag-1/ GM-Tg-rg-IP0600-Ag-2 Rat COX4I2 protein Rat
GM-Tg-mg-IP0600-Ag-1/ GM-Tg-mg-IP0600-Ag-2 Mouse COX4I2 protein Mouse
GM-Tg-cynog-IP0600-Ag-1/ GM-Tg-cynog-IP0600-Ag-2 Cynomolgus/Rhesus macaque COX4I2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0600-Ag-1/ GM-Tg-felg-IP0600-Ag-2 Feline COX4I2 protein Feline
GM-Tg-cang-IP0600-Ag-1/ GM-Tg-cang-IP0600-Ag-2 Canine COX4I2 protein Canine
GM-Tg-bovg-IP0600-Ag-1/ GM-Tg-bovg-IP0600-Ag-2 Bovine COX4I2 protein Bovine
GM-Tg-equg-IP0600-Ag-1/ GM-Tg-equg-IP0600-Ag-2 Equine COX4I2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0600-Ag-1/ GM-Tg-hg-IP0600-Ag-2; GM-Tg-rg-IP0600-Ag-1/ GM-Tg-rg-IP0600-Ag-2;
GM-Tg-mg-IP0600-Ag-1/ GM-Tg-mg-IP0600-Ag-2; GM-Tg-cynog-IP0600-Ag-1/ GM-Tg-cynog-IP0600-Ag-2;
GM-Tg-felg-IP0600-Ag-1/ GM-Tg-felg-IP0600-Ag-2; GM-Tg-cang-IP0600-Ag-1/ GM-Tg-cang-IP0600-Ag-2;
GM-Tg-bovg-IP0600-Ag-1/ GM-Tg-bovg-IP0600-Ag-2; GM-Tg-equg-IP0600-Ag-1/ GM-Tg-equg-IP0600-Ag-2
Products Name COX4I2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name COX4I2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX4I2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.