Recombinant multi-species COX11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. [provided by RefSeq, Jun 2009]
The Alternative Names of target: 2010004I09Rik,COX11,COX11P,Cox11,Cytochrome c oxidase assembly protein COX11,MC4DN23,mitochondrial

Target products collectionGo to COX11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0594-Ag-1/ GM-Tg-hg-IP0594-Ag-2 Human COX11 protein Human
GM-Tg-rg-IP0594-Ag-1/ GM-Tg-rg-IP0594-Ag-2 Rat COX11 protein Rat
GM-Tg-mg-IP0594-Ag-1/ GM-Tg-mg-IP0594-Ag-2 Mouse COX11 protein Mouse
GM-Tg-cynog-IP0594-Ag-1/ GM-Tg-cynog-IP0594-Ag-2 Cynomolgus/Rhesus macaque COX11 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0594-Ag-1/ GM-Tg-felg-IP0594-Ag-2 Feline COX11 protein Feline
GM-Tg-cang-IP0594-Ag-1/ GM-Tg-cang-IP0594-Ag-2 Canine COX11 protein Canine
GM-Tg-bovg-IP0594-Ag-1/ GM-Tg-bovg-IP0594-Ag-2 Bovine COX11 protein Bovine
GM-Tg-equg-IP0594-Ag-1/ GM-Tg-equg-IP0594-Ag-2 Equine COX11 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0594-Ag-1/ GM-Tg-hg-IP0594-Ag-2; GM-Tg-rg-IP0594-Ag-1/ GM-Tg-rg-IP0594-Ag-2;
GM-Tg-mg-IP0594-Ag-1/ GM-Tg-mg-IP0594-Ag-2; GM-Tg-cynog-IP0594-Ag-1/ GM-Tg-cynog-IP0594-Ag-2;
GM-Tg-felg-IP0594-Ag-1/ GM-Tg-felg-IP0594-Ag-2; GM-Tg-cang-IP0594-Ag-1/ GM-Tg-cang-IP0594-Ag-2;
GM-Tg-bovg-IP0594-Ag-1/ GM-Tg-bovg-IP0594-Ag-2; GM-Tg-equg-IP0594-Ag-1/ GM-Tg-equg-IP0594-Ag-2
Products Name COX11 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name COX11
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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