Recombinant multi-species Caspr2/CNTNAP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Caspr2/CNTNAP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability. [provided by RefSeq, Jul 2017]
The Alternative Names of target: 5430425M22Rik,AUTS15,CASPR,CASPR2,CDFE,CNTNAP2,Caspr2,Cell recognition molecule Caspr2,Cntnap2,Contactin-associated protein-like 2,NRXN4,PTHSL1,mKIAA0868
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0587-Ag-1/ GM-Tg-hg-IP0587-Ag-2 | Human Caspr2/CNTNAP2 protein | Human |
| GM-Tg-rg-IP0587-Ag-1/ GM-Tg-rg-IP0587-Ag-2 | Rat Caspr2/CNTNAP2 protein | Rat |
| GM-Tg-mg-IP0587-Ag-1/ GM-Tg-mg-IP0587-Ag-2 | Mouse Caspr2/CNTNAP2 protein | Mouse |
| GM-Tg-cynog-IP0587-Ag-1/ GM-Tg-cynog-IP0587-Ag-2 | Cynomolgus/Rhesus macaque Caspr2/CNTNAP2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0587-Ag-1/ GM-Tg-felg-IP0587-Ag-2 | Feline Caspr2/CNTNAP2 protein | Feline |
| GM-Tg-cang-IP0587-Ag-1/ GM-Tg-cang-IP0587-Ag-2 | Canine Caspr2/CNTNAP2 protein | Canine |
| GM-Tg-bovg-IP0587-Ag-1/ GM-Tg-bovg-IP0587-Ag-2 | Bovine Caspr2/CNTNAP2 protein | Bovine |
| GM-Tg-equg-IP0587-Ag-1/ GM-Tg-equg-IP0587-Ag-2 | Equine Caspr2/CNTNAP2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP0587-Ag-1/ GM-Tg-hg-IP0587-Ag-2;
GM-Tg-rg-IP0587-Ag-1/ GM-Tg-rg-IP0587-Ag-2;
GM-Tg-mg-IP0587-Ag-1/ GM-Tg-mg-IP0587-Ag-2; GM-Tg-cynog-IP0587-Ag-1/ GM-Tg-cynog-IP0587-Ag-2; GM-Tg-felg-IP0587-Ag-1/ GM-Tg-felg-IP0587-Ag-2; GM-Tg-cang-IP0587-Ag-1/ GM-Tg-cang-IP0587-Ag-2; GM-Tg-bovg-IP0587-Ag-1/ GM-Tg-bovg-IP0587-Ag-2; GM-Tg-equg-IP0587-Ag-1/ GM-Tg-equg-IP0587-Ag-2 |
| Products Name | Caspr2/CNTNAP2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Caspr2/CNTNAP2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Caspr2/CNTNAP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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GMab, developed by GeneMedi, constitutes an
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monoclonal antibodies, each meticulously
designed to target specific molecular
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.