Recombinant multi-species CASPR/CNTNAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CASPR/CNTNAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009]
The Alternative Names of target: CASPR, CNTNAP1,Contactin-associated protein 1,Caspr, Caspr1,Neurexin IV, Neurexin-4, p190,CHN3,P190,CASPR,NRXN4,CNTNAP
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP0586-Ab-1/ GM-Tg-hg-IP0586-Ab-2 | Human CASPR/CNTNAP1 protein | Human |
GM-Tg-rg-IP0586-Ab-1/ GM-Tg-rg-IP0586-Ab-2 | Rat CASPR/CNTNAP1 protein | Rat |
GM-Tg-mg-IP0586-Ab-1/ GM-Tg-mg-IP0586-Ab-2 | Mouse CASPR/CNTNAP1 protein | Mouse |
GM-Tg-cynog-IP0586-Ab-1/ GM-Tg-cynog-IP0586-Ab-2 | Cynomolgus/Rhesus macaque CASPR/CNTNAP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP0586-Ab-1/ GM-Tg-felg-IP0586-Ab-2 | Feline CASPR/CNTNAP1 protein | Feline |
GM-Tg-cang-IP0586-Ab-1/ GM-Tg-cang-IP0586-Ab-2 | Canine CASPR/CNTNAP1 protein | Canine |
GM-Tg-bovg-IP0586-Ab-1/ GM-Tg-bovg-IP0586-Ab-2 | Bovine CASPR/CNTNAP1 protein | Bovine |
GM-Tg-equg-IP0586-Ab-1/ GM-Tg-equg-IP0586-Ab-2 | Equine CASPR/CNTNAP1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-IP0586-Ab-1/ GM-Tg-hg-IP0586-Ab-2;
GM-Tg-rg-IP0586-Ab-1/ GM-Tg-rg-IP0586-Ab-2;
GM-Tg-mg-IP0586-Ab-1/ GM-Tg-mg-IP0586-Ab-2; GM-Tg-cynog-IP0586-Ab-1/ GM-Tg-cynog-IP0586-Ab-2; GM-Tg-felg-IP0586-Ab-1/ GM-Tg-felg-IP0586-Ab-2; GM-Tg-cang-IP0586-Ab-1/ GM-Tg-cang-IP0586-Ab-2; GM-Tg-bovg-IP0586-Ab-1/ GM-Tg-bovg-IP0586-Ab-2; GM-Tg-equg-IP0586-Ab-1/ GM-Tg-equg-IP0586-Ab-2 |
Products Name | CASPR/CNTNAP1 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | CASPR/CNTNAP1 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CASPR/CNTNAP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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