Recombinant multi-species CLN6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLN6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008]
The Alternative Names of target: 1810065L06Rik,CLN4A,CLN6,CLN6A,Ceroid-lipofuscinosis neuronal protein 6,Cln6,D9Bwg1455e,HsT18960,Protein CLN6,nclf

Target products collectionGo to CLN6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0562-Ag-1/ GM-Tg-hg-IP0562-Ag-2 Human CLN6 protein Human
GM-Tg-rg-IP0562-Ag-1/ GM-Tg-rg-IP0562-Ag-2 Rat CLN6 protein Rat
GM-Tg-mg-IP0562-Ag-1/ GM-Tg-mg-IP0562-Ag-2 Mouse CLN6 protein Mouse
GM-Tg-cynog-IP0562-Ag-1/ GM-Tg-cynog-IP0562-Ag-2 Cynomolgus/Rhesus macaque CLN6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0562-Ag-1/ GM-Tg-felg-IP0562-Ag-2 Feline CLN6 protein Feline
GM-Tg-cang-IP0562-Ag-1/ GM-Tg-cang-IP0562-Ag-2 Canine CLN6 protein Canine
GM-Tg-bovg-IP0562-Ag-1/ GM-Tg-bovg-IP0562-Ag-2 Bovine CLN6 protein Bovine
GM-Tg-equg-IP0562-Ag-1/ GM-Tg-equg-IP0562-Ag-2 Equine CLN6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0562-Ag-1/ GM-Tg-hg-IP0562-Ag-2; GM-Tg-rg-IP0562-Ag-1/ GM-Tg-rg-IP0562-Ag-2;
GM-Tg-mg-IP0562-Ag-1/ GM-Tg-mg-IP0562-Ag-2; GM-Tg-cynog-IP0562-Ag-1/ GM-Tg-cynog-IP0562-Ag-2;
GM-Tg-felg-IP0562-Ag-1/ GM-Tg-felg-IP0562-Ag-2; GM-Tg-cang-IP0562-Ag-1/ GM-Tg-cang-IP0562-Ag-2;
GM-Tg-bovg-IP0562-Ag-1/ GM-Tg-bovg-IP0562-Ag-2; GM-Tg-equg-IP0562-Ag-1/ GM-Tg-equg-IP0562-Ag-2
Products Name CLN6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CLN6
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLN6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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