Recombinant multi-species CHRNB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHRNB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ACHRB,Acetylcholine receptor subunit beta,Achr-2,Acrb,CHRNB,CHRNB1,CMS1D,CMS2A,CMS2C,Chrnb1,RNACRB1,SCCMS,nAChR

Target products collectionGo to CHRNB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0545-Ag-1/ GM-Tg-hg-IP0545-Ag-2 Human CHRNB1 protein Human
GM-Tg-rg-IP0545-Ag-1/ GM-Tg-rg-IP0545-Ag-2 Rat CHRNB1 protein Rat
GM-Tg-mg-IP0545-Ag-1/ GM-Tg-mg-IP0545-Ag-2 Mouse CHRNB1 protein Mouse
GM-Tg-cynog-IP0545-Ag-1/ GM-Tg-cynog-IP0545-Ag-2 Cynomolgus/Rhesus macaque CHRNB1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0545-Ag-1/ GM-Tg-felg-IP0545-Ag-2 Feline CHRNB1 protein Feline
GM-Tg-cang-IP0545-Ag-1/ GM-Tg-cang-IP0545-Ag-2 Canine CHRNB1 protein Canine
GM-Tg-bovg-IP0545-Ag-1/ GM-Tg-bovg-IP0545-Ag-2 Bovine CHRNB1 protein Bovine
GM-Tg-equg-IP0545-Ag-1/ GM-Tg-equg-IP0545-Ag-2 Equine CHRNB1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0545-Ag-1/ GM-Tg-hg-IP0545-Ag-2; GM-Tg-rg-IP0545-Ag-1/ GM-Tg-rg-IP0545-Ag-2;
GM-Tg-mg-IP0545-Ag-1/ GM-Tg-mg-IP0545-Ag-2; GM-Tg-cynog-IP0545-Ag-1/ GM-Tg-cynog-IP0545-Ag-2;
GM-Tg-felg-IP0545-Ag-1/ GM-Tg-felg-IP0545-Ag-2; GM-Tg-cang-IP0545-Ag-1/ GM-Tg-cang-IP0545-Ag-2;
GM-Tg-bovg-IP0545-Ag-1/ GM-Tg-bovg-IP0545-Ag-2; GM-Tg-equg-IP0545-Ag-1/ GM-Tg-equg-IP0545-Ag-2
Products Name CHRNB1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CHRNB1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHRNB1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.