Recombinant multi-species LASS2/CERS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LASS2/CERS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 0610013I17Rik,CERS2,CerS2,Ceramide synthase 2,Cers2,L3,LAG1 longevity assurance homolog 2,LASS2,Lass2,SP260,Sphingosine N-acyltransferase CERS2,TMSG1,TRH3,Tumor metastasis-suppressor gene 1 protein,Very-long-chain ceramide synthase CERS2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0534-Ag-1/ GM-Tg-hg-IP0534-Ag-2 | Human LASS2/CERS2 protein | Human |
| GM-Tg-rg-IP0534-Ag-1/ GM-Tg-rg-IP0534-Ag-2 | Rat LASS2/CERS2 protein | Rat |
| GM-Tg-mg-IP0534-Ag-1/ GM-Tg-mg-IP0534-Ag-2 | Mouse LASS2/CERS2 protein | Mouse |
| GM-Tg-cynog-IP0534-Ag-1/ GM-Tg-cynog-IP0534-Ag-2 | Cynomolgus/Rhesus macaque LASS2/CERS2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0534-Ag-1/ GM-Tg-felg-IP0534-Ag-2 | Feline LASS2/CERS2 protein | Feline |
| GM-Tg-cang-IP0534-Ag-1/ GM-Tg-cang-IP0534-Ag-2 | Canine LASS2/CERS2 protein | Canine |
| GM-Tg-bovg-IP0534-Ag-1/ GM-Tg-bovg-IP0534-Ag-2 | Bovine LASS2/CERS2 protein | Bovine |
| GM-Tg-equg-IP0534-Ag-1/ GM-Tg-equg-IP0534-Ag-2 | Equine LASS2/CERS2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP0534-Ag-1/ GM-Tg-hg-IP0534-Ag-2;
GM-Tg-rg-IP0534-Ag-1/ GM-Tg-rg-IP0534-Ag-2;
GM-Tg-mg-IP0534-Ag-1/ GM-Tg-mg-IP0534-Ag-2; GM-Tg-cynog-IP0534-Ag-1/ GM-Tg-cynog-IP0534-Ag-2; GM-Tg-felg-IP0534-Ag-1/ GM-Tg-felg-IP0534-Ag-2; GM-Tg-cang-IP0534-Ag-1/ GM-Tg-cang-IP0534-Ag-2; GM-Tg-bovg-IP0534-Ag-1/ GM-Tg-bovg-IP0534-Ag-2; GM-Tg-equg-IP0534-Ag-1/ GM-Tg-equg-IP0534-Ag-2 |
| Products Name | LASS2/CERS2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | LASS2/CERS2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LASS2/CERS2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.