Recombinant multi-species AKAP6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AKAP6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AKAP6,A-kinase anchor protein 6,AKAP-6,A-kinase anchor protein 100 kDa (AKAP 100), Protein kinase A-anchoring protein 6 (PRKA6), mAKAP,ADAP6,PRKA6,mAKAP,ADAP100,AKAP100
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP0311-Ab-1/ GM-Tg-hg-IP0311-Ab-2 | Human AKAP6 protein | Human |
GM-Tg-rg-IP0311-Ab-1/ GM-Tg-rg-IP0311-Ab-2 | Rat AKAP6 protein | Rat |
GM-Tg-mg-IP0311-Ab-1/ GM-Tg-mg-IP0311-Ab-2 | Mouse AKAP6 protein | Mouse |
GM-Tg-cynog-IP0311-Ab-1/ GM-Tg-cynog-IP0311-Ab-2 | Cynomolgus/Rhesus macaque AKAP6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP0311-Ab-1/ GM-Tg-felg-IP0311-Ab-2 | Feline AKAP6 protein | Feline |
GM-Tg-cang-IP0311-Ab-1/ GM-Tg-cang-IP0311-Ab-2 | Canine AKAP6 protein | Canine |
GM-Tg-bovg-IP0311-Ab-1/ GM-Tg-bovg-IP0311-Ab-2 | Bovine AKAP6 protein | Bovine |
GM-Tg-equg-IP0311-Ab-1/ GM-Tg-equg-IP0311-Ab-2 | Equine AKAP6 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-IP0311-Ab-1/ GM-Tg-hg-IP0311-Ab-2;
GM-Tg-rg-IP0311-Ab-1/ GM-Tg-rg-IP0311-Ab-2;
GM-Tg-mg-IP0311-Ab-1/ GM-Tg-mg-IP0311-Ab-2; GM-Tg-cynog-IP0311-Ab-1/ GM-Tg-cynog-IP0311-Ab-2; GM-Tg-felg-IP0311-Ab-1/ GM-Tg-felg-IP0311-Ab-2; GM-Tg-cang-IP0311-Ab-1/ GM-Tg-cang-IP0311-Ab-2; GM-Tg-bovg-IP0311-Ab-1/ GM-Tg-bovg-IP0311-Ab-2; GM-Tg-equg-IP0311-Ab-1/ GM-Tg-equg-IP0311-Ab-2 |
Products Name | AKAP6 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | AKAP6 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AKAP6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.