Recombinant multi-species ABCD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ABCD1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ABC42,ABCD1,ALD,ALDP,AMN,ATP-binding cassette sub-family D member 1,Abcd1,Adrenoleukodystrophy protein (ALDP),Ald,Aldgh,RGD1562128

Target products collectionGo to ABCD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0281-Ag-1/ GM-Tg-hg-IP0281-Ag-2 Human ABCD1 protein Human
GM-Tg-rg-IP0281-Ag-1/ GM-Tg-rg-IP0281-Ag-2 Rat ABCD1 protein Rat
GM-Tg-mg-IP0281-Ag-1/ GM-Tg-mg-IP0281-Ag-2 Mouse ABCD1 protein Mouse
GM-Tg-cynog-IP0281-Ag-1/ GM-Tg-cynog-IP0281-Ag-2 Cynomolgus/Rhesus macaque ABCD1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0281-Ag-1/ GM-Tg-felg-IP0281-Ag-2 Feline ABCD1 protein Feline
GM-Tg-cang-IP0281-Ag-1/ GM-Tg-cang-IP0281-Ag-2 Canine ABCD1 protein Canine
GM-Tg-bovg-IP0281-Ag-1/ GM-Tg-bovg-IP0281-Ag-2 Bovine ABCD1 protein Bovine
GM-Tg-equg-IP0281-Ag-1/ GM-Tg-equg-IP0281-Ag-2 Equine ABCD1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0281-Ag-1/ GM-Tg-hg-IP0281-Ag-2; GM-Tg-rg-IP0281-Ag-1/ GM-Tg-rg-IP0281-Ag-2;
GM-Tg-mg-IP0281-Ag-1/ GM-Tg-mg-IP0281-Ag-2; GM-Tg-cynog-IP0281-Ag-1/ GM-Tg-cynog-IP0281-Ag-2;
GM-Tg-felg-IP0281-Ag-1/ GM-Tg-felg-IP0281-Ag-2; GM-Tg-cang-IP0281-Ag-1/ GM-Tg-cang-IP0281-Ag-2;
GM-Tg-bovg-IP0281-Ag-1/ GM-Tg-bovg-IP0281-Ag-2; GM-Tg-equg-IP0281-Ag-1/ GM-Tg-equg-IP0281-Ag-2
Products Name ABCD1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ABCD1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ABCD1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.