Recombinant multi-species AATK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AATK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
The Alternative Names of target: AATK,Serine/threonine-protein kinase LMTK1,Apoptosis-associated tyrosine kinase (AATYK), Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein (p35BP),LMR1,AATYK,LMTK1,p35BP,AATYK1,PPP1R77

Target products collectionGo to AATK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0273-Ab-1/ GM-Tg-hg-IP0273-Ab-2 Human AATK protein Human
GM-Tg-rg-IP0273-Ab-1/ GM-Tg-rg-IP0273-Ab-2 Rat AATK protein Rat
GM-Tg-mg-IP0273-Ab-1/ GM-Tg-mg-IP0273-Ab-2 Mouse AATK protein Mouse
GM-Tg-cynog-IP0273-Ab-1/ GM-Tg-cynog-IP0273-Ab-2 Cynomolgus/Rhesus macaque AATK monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0273-Ab-1/ GM-Tg-felg-IP0273-Ab-2 Feline AATK protein Feline
GM-Tg-cang-IP0273-Ab-1/ GM-Tg-cang-IP0273-Ab-2 Canine AATK protein Canine
GM-Tg-bovg-IP0273-Ab-1/ GM-Tg-bovg-IP0273-Ab-2 Bovine AATK protein Bovine
GM-Tg-equg-IP0273-Ab-1/ GM-Tg-equg-IP0273-Ab-2 Equine AATK protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0273-Ab-1/ GM-Tg-hg-IP0273-Ab-2; GM-Tg-rg-IP0273-Ab-1/ GM-Tg-rg-IP0273-Ab-2;
GM-Tg-mg-IP0273-Ab-1/ GM-Tg-mg-IP0273-Ab-2; GM-Tg-cynog-IP0273-Ab-1/ GM-Tg-cynog-IP0273-Ab-2;
GM-Tg-felg-IP0273-Ab-1/ GM-Tg-felg-IP0273-Ab-2; GM-Tg-cang-IP0273-Ab-1/ GM-Tg-cang-IP0273-Ab-2;
GM-Tg-bovg-IP0273-Ab-1/ GM-Tg-bovg-IP0273-Ab-2; GM-Tg-equg-IP0273-Ab-1/ GM-Tg-equg-IP0273-Ab-2
Products Name AATK protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AATK
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AATK protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.