Recombinant multi-species Connexin-46/GJA3/Cx46 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Connexin-46/GJA3/Cx46 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a connexin and is a component of lens fiber gap junctions. Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3). [provided by RefSeq, Jan 2010]
The Alternative Names of target: CTRCT14,CX46,CXNJ1,CZP3,Cnx46,Connexin-46,Connexin-46 (Cx46),Cx43,Cx46,Cxnj1,GJA3,Gap junction alpha-3 protein,Gja-3,Gja3

Target products collectionGo to Connexin-46/GJA3/Cx46 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0223-Ag-1/ GM-Tg-hg-IP0223-Ag-2 Human Connexin-46/GJA3/Cx46 protein Human
GM-Tg-rg-IP0223-Ag-1/ GM-Tg-rg-IP0223-Ag-2 Rat Connexin-46/GJA3/Cx46 protein Rat
GM-Tg-mg-IP0223-Ag-1/ GM-Tg-mg-IP0223-Ag-2 Mouse Connexin-46/GJA3/Cx46 protein Mouse
GM-Tg-cynog-IP0223-Ag-1/ GM-Tg-cynog-IP0223-Ag-2 Cynomolgus/Rhesus macaque Connexin-46/GJA3/Cx46 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0223-Ag-1/ GM-Tg-felg-IP0223-Ag-2 Feline Connexin-46/GJA3/Cx46 protein Feline
GM-Tg-cang-IP0223-Ag-1/ GM-Tg-cang-IP0223-Ag-2 Canine Connexin-46/GJA3/Cx46 protein Canine
GM-Tg-bovg-IP0223-Ag-1/ GM-Tg-bovg-IP0223-Ag-2 Bovine Connexin-46/GJA3/Cx46 protein Bovine
GM-Tg-equg-IP0223-Ag-1/ GM-Tg-equg-IP0223-Ag-2 Equine Connexin-46/GJA3/Cx46 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0223-Ag-1/ GM-Tg-hg-IP0223-Ag-2; GM-Tg-rg-IP0223-Ag-1/ GM-Tg-rg-IP0223-Ag-2;
GM-Tg-mg-IP0223-Ag-1/ GM-Tg-mg-IP0223-Ag-2; GM-Tg-cynog-IP0223-Ag-1/ GM-Tg-cynog-IP0223-Ag-2;
GM-Tg-felg-IP0223-Ag-1/ GM-Tg-felg-IP0223-Ag-2; GM-Tg-cang-IP0223-Ag-1/ GM-Tg-cang-IP0223-Ag-2;
GM-Tg-bovg-IP0223-Ag-1/ GM-Tg-bovg-IP0223-Ag-2; GM-Tg-equg-IP0223-Ag-1/ GM-Tg-equg-IP0223-Ag-2
Products Name Connexin-46/GJA3/Cx46 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Connexin-46/GJA3/Cx46
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Connexin-46/GJA3/Cx46 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.