Recombinant multi-species TPCN2/TPC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPCN2/TPC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009]
The Alternative Names of target: TPCN2, TPC2,Two pore channel protein 2,Two pore calcium channel protein 2,TPC2,SHEP10

Target products collectionGo to TPCN2/TPC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0206-Ab-1/ GM-Tg-hg-IP0206-Ab-2 Human TPCN2/TPC2 protein Human
GM-Tg-rg-IP0206-Ab-1/ GM-Tg-rg-IP0206-Ab-2 Rat TPCN2/TPC2 protein Rat
GM-Tg-mg-IP0206-Ab-1/ GM-Tg-mg-IP0206-Ab-2 Mouse TPCN2/TPC2 protein Mouse
GM-Tg-cynog-IP0206-Ab-1/ GM-Tg-cynog-IP0206-Ab-2 Cynomolgus/Rhesus macaque TPCN2/TPC2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0206-Ab-1/ GM-Tg-felg-IP0206-Ab-2 Feline TPCN2/TPC2 protein Feline
GM-Tg-cang-IP0206-Ab-1/ GM-Tg-cang-IP0206-Ab-2 Canine TPCN2/TPC2 protein Canine
GM-Tg-bovg-IP0206-Ab-1/ GM-Tg-bovg-IP0206-Ab-2 Bovine TPCN2/TPC2 protein Bovine
GM-Tg-equg-IP0206-Ab-1/ GM-Tg-equg-IP0206-Ab-2 Equine TPCN2/TPC2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0206-Ab-1/ GM-Tg-hg-IP0206-Ab-2; GM-Tg-rg-IP0206-Ab-1/ GM-Tg-rg-IP0206-Ab-2;
GM-Tg-mg-IP0206-Ab-1/ GM-Tg-mg-IP0206-Ab-2; GM-Tg-cynog-IP0206-Ab-1/ GM-Tg-cynog-IP0206-Ab-2;
GM-Tg-felg-IP0206-Ab-1/ GM-Tg-felg-IP0206-Ab-2; GM-Tg-cang-IP0206-Ab-1/ GM-Tg-cang-IP0206-Ab-2;
GM-Tg-bovg-IP0206-Ab-1/ GM-Tg-bovg-IP0206-Ab-2; GM-Tg-equg-IP0206-Ab-1/ GM-Tg-equg-IP0206-Ab-2
Products Name TPCN2/TPC2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TPCN2/TPC2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPCN2/TPC2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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