Recombinant multi-species GJA5/Connexin 40/Cx40 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GJA5/Connexin 40/Cx40 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5730555N10Rik,ATFB11,CX40,CXNI,Cnx40,Connexin 40,Connexin-40 (Cx40),Cx40,Cxni,GJA5,Gap junction alpha-5 protein,Gja-5,Gja5
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0181-Ag-1/ GM-Tg-hg-IP0181-Ag-2 | Human GJA5/Connexin 40/Cx40 protein | Human |
| GM-Tg-rg-IP0181-Ag-1/ GM-Tg-rg-IP0181-Ag-2 | Rat GJA5/Connexin 40/Cx40 protein | Rat |
| GM-Tg-mg-IP0181-Ag-1/ GM-Tg-mg-IP0181-Ag-2 | Mouse GJA5/Connexin 40/Cx40 protein | Mouse |
| GM-Tg-cynog-IP0181-Ag-1/ GM-Tg-cynog-IP0181-Ag-2 | Cynomolgus/Rhesus macaque GJA5/Connexin 40/Cx40 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0181-Ag-1/ GM-Tg-felg-IP0181-Ag-2 | Feline GJA5/Connexin 40/Cx40 protein | Feline |
| GM-Tg-cang-IP0181-Ag-1/ GM-Tg-cang-IP0181-Ag-2 | Canine GJA5/Connexin 40/Cx40 protein | Canine |
| GM-Tg-bovg-IP0181-Ag-1/ GM-Tg-bovg-IP0181-Ag-2 | Bovine GJA5/Connexin 40/Cx40 protein | Bovine |
| GM-Tg-equg-IP0181-Ag-1/ GM-Tg-equg-IP0181-Ag-2 | Equine GJA5/Connexin 40/Cx40 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP0181-Ag-1/ GM-Tg-hg-IP0181-Ag-2;
GM-Tg-rg-IP0181-Ag-1/ GM-Tg-rg-IP0181-Ag-2;
GM-Tg-mg-IP0181-Ag-1/ GM-Tg-mg-IP0181-Ag-2; GM-Tg-cynog-IP0181-Ag-1/ GM-Tg-cynog-IP0181-Ag-2; GM-Tg-felg-IP0181-Ag-1/ GM-Tg-felg-IP0181-Ag-2; GM-Tg-cang-IP0181-Ag-1/ GM-Tg-cang-IP0181-Ag-2; GM-Tg-bovg-IP0181-Ag-1/ GM-Tg-bovg-IP0181-Ag-2; GM-Tg-equg-IP0181-Ag-1/ GM-Tg-equg-IP0181-Ag-2 |
| Products Name | GJA5/Connexin 40/Cx40 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | GJA5/Connexin 40/Cx40 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GJA5/Connexin 40/Cx40 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
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(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.