Recombinant multi-species UBE1/UBA1/UBAE1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UBE1/UBA1/UBAE1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
The Alternative Names of target: A1S9,A1S9T,A1ST,AMCX1,CFAP124,GXP1,POC20,Protein A1S9,SMAX2,Sbx,UBA1,UBA1A,UBAE1,UBE1,UBE1X,Uba1,Ube-1,Ube1x,Ubiquitin-activating enzyme E1,Ubiquitin-like modifier-activating enzyme 1,VEXAS

Target products collectionGo to UBE1/UBA1/UBAE1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0143-Ag-1/ GM-Tg-hg-IP0143-Ag-2 Human UBE1/UBA1/UBAE1 protein Human
GM-Tg-rg-IP0143-Ag-1/ GM-Tg-rg-IP0143-Ag-2 Rat UBE1/UBA1/UBAE1 protein Rat
GM-Tg-mg-IP0143-Ag-1/ GM-Tg-mg-IP0143-Ag-2 Mouse UBE1/UBA1/UBAE1 protein Mouse
GM-Tg-cynog-IP0143-Ag-1/ GM-Tg-cynog-IP0143-Ag-2 Cynomolgus/Rhesus macaque UBE1/UBA1/UBAE1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0143-Ag-1/ GM-Tg-felg-IP0143-Ag-2 Feline UBE1/UBA1/UBAE1 protein Feline
GM-Tg-cang-IP0143-Ag-1/ GM-Tg-cang-IP0143-Ag-2 Canine UBE1/UBA1/UBAE1 protein Canine
GM-Tg-bovg-IP0143-Ag-1/ GM-Tg-bovg-IP0143-Ag-2 Bovine UBE1/UBA1/UBAE1 protein Bovine
GM-Tg-equg-IP0143-Ag-1/ GM-Tg-equg-IP0143-Ag-2 Equine UBE1/UBA1/UBAE1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0143-Ag-1/ GM-Tg-hg-IP0143-Ag-2; GM-Tg-rg-IP0143-Ag-1/ GM-Tg-rg-IP0143-Ag-2;
GM-Tg-mg-IP0143-Ag-1/ GM-Tg-mg-IP0143-Ag-2; GM-Tg-cynog-IP0143-Ag-1/ GM-Tg-cynog-IP0143-Ag-2;
GM-Tg-felg-IP0143-Ag-1/ GM-Tg-felg-IP0143-Ag-2; GM-Tg-cang-IP0143-Ag-1/ GM-Tg-cang-IP0143-Ag-2;
GM-Tg-bovg-IP0143-Ag-1/ GM-Tg-bovg-IP0143-Ag-2; GM-Tg-equg-IP0143-Ag-1/ GM-Tg-equg-IP0143-Ag-2
Products Name UBE1/UBA1/UBAE1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name UBE1/UBA1/UBAE1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UBE1/UBA1/UBAE1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.