Recombinant multi-species DHCR24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHCR24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2310076D10Rik,24-dehydrocholesterol reductase,3-beta-hydroxysterol Delta-24-reductase,5830417J06Rik,DCE,DHCR24,Delta(24)-sterol reductase,Dhcr24,Diminuto/dwarf1 homolog,Nbla03646,SELADIN1,Seladin-1,mKIAA0018,seladin-1

Target products collectionGo to DHCR24 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0124-Ag-1/ GM-Tg-hg-IP0124-Ag-2 Human DHCR24 protein Human
GM-Tg-rg-IP0124-Ag-1/ GM-Tg-rg-IP0124-Ag-2 Rat DHCR24 protein Rat
GM-Tg-mg-IP0124-Ag-1/ GM-Tg-mg-IP0124-Ag-2 Mouse DHCR24 protein Mouse
GM-Tg-cynog-IP0124-Ag-1/ GM-Tg-cynog-IP0124-Ag-2 Cynomolgus/Rhesus macaque DHCR24 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0124-Ag-1/ GM-Tg-felg-IP0124-Ag-2 Feline DHCR24 protein Feline
GM-Tg-cang-IP0124-Ag-1/ GM-Tg-cang-IP0124-Ag-2 Canine DHCR24 protein Canine
GM-Tg-bovg-IP0124-Ag-1/ GM-Tg-bovg-IP0124-Ag-2 Bovine DHCR24 protein Bovine
GM-Tg-equg-IP0124-Ag-1/ GM-Tg-equg-IP0124-Ag-2 Equine DHCR24 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0124-Ag-1/ GM-Tg-hg-IP0124-Ag-2; GM-Tg-rg-IP0124-Ag-1/ GM-Tg-rg-IP0124-Ag-2;
GM-Tg-mg-IP0124-Ag-1/ GM-Tg-mg-IP0124-Ag-2; GM-Tg-cynog-IP0124-Ag-1/ GM-Tg-cynog-IP0124-Ag-2;
GM-Tg-felg-IP0124-Ag-1/ GM-Tg-felg-IP0124-Ag-2; GM-Tg-cang-IP0124-Ag-1/ GM-Tg-cang-IP0124-Ag-2;
GM-Tg-bovg-IP0124-Ag-1/ GM-Tg-bovg-IP0124-Ag-2; GM-Tg-equg-IP0124-Ag-1/ GM-Tg-equg-IP0124-Ag-2
Products Name DHCR24 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DHCR24
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DHCR24 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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