Recombinant multi-species DCLK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DCLK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010]
The Alternative Names of target: 1700113D08Rik,2810480F11Rik,Ania4,CL1,CLICK1,Click-I,Cpg16,DCAMKL1,DCDC3A,DCLK,DCLK1,Dcamkl1,Dcl,Dclk,Dclk1,Doublecortin domain-containing protein 3A,Doublecortin-like and CAM kinase-like 1,Doublecortin-like kinase 1,Serine/threonine-protein kinase DCLK1,mKIAA0369

Target products collectionGo to DCLK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0115-Ag-1/ GM-Tg-hg-IP0115-Ag-2 Human DCLK1 protein Human
GM-Tg-rg-IP0115-Ag-1/ GM-Tg-rg-IP0115-Ag-2 Rat DCLK1 protein Rat
GM-Tg-mg-IP0115-Ag-1/ GM-Tg-mg-IP0115-Ag-2 Mouse DCLK1 protein Mouse
GM-Tg-cynog-IP0115-Ag-1/ GM-Tg-cynog-IP0115-Ag-2 Cynomolgus/Rhesus macaque DCLK1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0115-Ag-1/ GM-Tg-felg-IP0115-Ag-2 Feline DCLK1 protein Feline
GM-Tg-cang-IP0115-Ag-1/ GM-Tg-cang-IP0115-Ag-2 Canine DCLK1 protein Canine
GM-Tg-bovg-IP0115-Ag-1/ GM-Tg-bovg-IP0115-Ag-2 Bovine DCLK1 protein Bovine
GM-Tg-equg-IP0115-Ag-1/ GM-Tg-equg-IP0115-Ag-2 Equine DCLK1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0115-Ag-1/ GM-Tg-hg-IP0115-Ag-2; GM-Tg-rg-IP0115-Ag-1/ GM-Tg-rg-IP0115-Ag-2;
GM-Tg-mg-IP0115-Ag-1/ GM-Tg-mg-IP0115-Ag-2; GM-Tg-cynog-IP0115-Ag-1/ GM-Tg-cynog-IP0115-Ag-2;
GM-Tg-felg-IP0115-Ag-1/ GM-Tg-felg-IP0115-Ag-2; GM-Tg-cang-IP0115-Ag-1/ GM-Tg-cang-IP0115-Ag-2;
GM-Tg-bovg-IP0115-Ag-1/ GM-Tg-bovg-IP0115-Ag-2; GM-Tg-equg-IP0115-Ag-1/ GM-Tg-equg-IP0115-Ag-2
Products Name DCLK1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DCLK1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DCLK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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