Recombinant multi-species HDAC10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
The Alternative Names of target: HD10,HDAC10,Hd10,Hdac10,Histone deacetylase 10 (HD10),Polyamine deacetylase HDAC10

Target products collectionGo to HDAC10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0086-Ag-1/ GM-Tg-hg-IP0086-Ag-2 Human HDAC10 protein Human
GM-Tg-rg-IP0086-Ag-1/ GM-Tg-rg-IP0086-Ag-2 Rat HDAC10 protein Rat
GM-Tg-mg-IP0086-Ag-1/ GM-Tg-mg-IP0086-Ag-2 Mouse HDAC10 protein Mouse
GM-Tg-cynog-IP0086-Ag-1/ GM-Tg-cynog-IP0086-Ag-2 Cynomolgus/Rhesus macaque HDAC10 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0086-Ag-1/ GM-Tg-felg-IP0086-Ag-2 Feline HDAC10 protein Feline
GM-Tg-cang-IP0086-Ag-1/ GM-Tg-cang-IP0086-Ag-2 Canine HDAC10 protein Canine
GM-Tg-bovg-IP0086-Ag-1/ GM-Tg-bovg-IP0086-Ag-2 Bovine HDAC10 protein Bovine
GM-Tg-equg-IP0086-Ag-1/ GM-Tg-equg-IP0086-Ag-2 Equine HDAC10 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0086-Ag-1/ GM-Tg-hg-IP0086-Ag-2; GM-Tg-rg-IP0086-Ag-1/ GM-Tg-rg-IP0086-Ag-2;
GM-Tg-mg-IP0086-Ag-1/ GM-Tg-mg-IP0086-Ag-2; GM-Tg-cynog-IP0086-Ag-1/ GM-Tg-cynog-IP0086-Ag-2;
GM-Tg-felg-IP0086-Ag-1/ GM-Tg-felg-IP0086-Ag-2; GM-Tg-cang-IP0086-Ag-1/ GM-Tg-cang-IP0086-Ag-2;
GM-Tg-bovg-IP0086-Ag-1/ GM-Tg-bovg-IP0086-Ag-2; GM-Tg-equg-IP0086-Ag-1/ GM-Tg-equg-IP0086-Ag-2
Products Name HDAC10 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HDAC10
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC10 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.