Recombinant multi-species CHRNA10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHRNA10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Predicted to enable acetylcholine-gated cation-selective channel activity. Acts upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be located in membrane. Predicted to be active in cholinergic synapse and neuron projection. Predicted to be integral component of postsynaptic specialization membrane.
The Alternative Names of target: CHRNA10,Neuronal acetylcholine receptor subunit alpha-10,Nicotinic acetylcholine receptor subunit alpha-10 (NACHR alpha-10)
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP0071-Ab-1/ GM-Tg-hg-IP0071-Ab-2 | Human CHRNA10 protein | Human |
GM-Tg-rg-IP0071-Ab-1/ GM-Tg-rg-IP0071-Ab-2 | Rat CHRNA10 protein | Rat |
GM-Tg-mg-IP0071-Ab-1/ GM-Tg-mg-IP0071-Ab-2 | Mouse CHRNA10 protein | Mouse |
GM-Tg-cynog-IP0071-Ab-1/ GM-Tg-cynog-IP0071-Ab-2 | Cynomolgus/Rhesus macaque CHRNA10 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP0071-Ab-1/ GM-Tg-felg-IP0071-Ab-2 | Feline CHRNA10 protein | Feline |
GM-Tg-cang-IP0071-Ab-1/ GM-Tg-cang-IP0071-Ab-2 | Canine CHRNA10 protein | Canine |
GM-Tg-bovg-IP0071-Ab-1/ GM-Tg-bovg-IP0071-Ab-2 | Bovine CHRNA10 protein | Bovine |
GM-Tg-equg-IP0071-Ab-1/ GM-Tg-equg-IP0071-Ab-2 | Equine CHRNA10 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-IP0071-Ab-1/ GM-Tg-hg-IP0071-Ab-2;
GM-Tg-rg-IP0071-Ab-1/ GM-Tg-rg-IP0071-Ab-2;
GM-Tg-mg-IP0071-Ab-1/ GM-Tg-mg-IP0071-Ab-2; GM-Tg-cynog-IP0071-Ab-1/ GM-Tg-cynog-IP0071-Ab-2; GM-Tg-felg-IP0071-Ab-1/ GM-Tg-felg-IP0071-Ab-2; GM-Tg-cang-IP0071-Ab-1/ GM-Tg-cang-IP0071-Ab-2; GM-Tg-bovg-IP0071-Ab-1/ GM-Tg-bovg-IP0071-Ab-2; GM-Tg-equg-IP0071-Ab-1/ GM-Tg-equg-IP0071-Ab-2 |
Products Name | CHRNA10 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | CHRNA10 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHRNA10 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.