Recombinant multi-species PTGES protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTGES protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2410099E23Rik,D2Ertd369e,Glutathione peroxidase PTGES,Glutathione transferase PTGES,MGST-IV,MGST1-L1,MGST1L1,MPGES,MPGES-1,Microsomal glutathione S-transferase 1-like 1 (MGST1-L1),Microsomal prostaglandin E synthase 1 (MPGES-1),PGES,PIG12,PP102,PP1294,PTGES,Pges,Prostaglandin E synthase,Ptges,TP53I12,mPGES,mPGES-1,p53-induced gene 12 protein

Target products collectionGo to PTGES products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0039-Ag-1/ GM-Tg-hg-IP0039-Ag-2 Human PTGES protein Human
GM-Tg-rg-IP0039-Ag-1/ GM-Tg-rg-IP0039-Ag-2 Rat PTGES protein Rat
GM-Tg-mg-IP0039-Ag-1/ GM-Tg-mg-IP0039-Ag-2 Mouse PTGES protein Mouse
GM-Tg-cynog-IP0039-Ag-1/ GM-Tg-cynog-IP0039-Ag-2 Cynomolgus/Rhesus macaque PTGES protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0039-Ag-1/ GM-Tg-felg-IP0039-Ag-2 Feline PTGES protein Feline
GM-Tg-cang-IP0039-Ag-1/ GM-Tg-cang-IP0039-Ag-2 Canine PTGES protein Canine
GM-Tg-bovg-IP0039-Ag-1/ GM-Tg-bovg-IP0039-Ag-2 Bovine PTGES protein Bovine
GM-Tg-equg-IP0039-Ag-1/ GM-Tg-equg-IP0039-Ag-2 Equine PTGES protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0039-Ag-1/ GM-Tg-hg-IP0039-Ag-2; GM-Tg-rg-IP0039-Ag-1/ GM-Tg-rg-IP0039-Ag-2;
GM-Tg-mg-IP0039-Ag-1/ GM-Tg-mg-IP0039-Ag-2; GM-Tg-cynog-IP0039-Ag-1/ GM-Tg-cynog-IP0039-Ag-2;
GM-Tg-felg-IP0039-Ag-1/ GM-Tg-felg-IP0039-Ag-2; GM-Tg-cang-IP0039-Ag-1/ GM-Tg-cang-IP0039-Ag-2;
GM-Tg-bovg-IP0039-Ag-1/ GM-Tg-bovg-IP0039-Ag-2; GM-Tg-equg-IP0039-Ag-1/ GM-Tg-equg-IP0039-Ag-2
Products Name PTGES protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PTGES
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTGES protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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